Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.
213 records found | Showing page 1 of 9 (records 1-25) | Number of records to display | Find orthologs in
Organism | Name | Ortholog group | Product |
---|---|---|---|
M. tuberculosis | Rv2247 | OG5_237713 | Acetyl/propionyl-CoA carboxylase (beta subunit) AccD6 |
M. tuberculosis | Rv1862 | OG5_126661 | Probable alcohol dehydrogenase AdhA |
M. tuberculosis | Rv3045 | OG5_126661 | Probable NADP-dependent alcohol dehydrogenase AdhC |
M. tuberculosis | Rv3086 | OG5_127257 | Probable zinc-type alcohol dehydrogenase AdhD (aldehyde reductase) |
M. tuberculosis | Rv2471 | OG5_126827 | Probable alpha-glucosidase AglA (maltase) (glucoinvertase) (glucosidosucrase) (m ... |
M. tuberculosis | Rv0768 | OG5_127004 | Probable aldehyde dehydrogenase NAD dependent AldA (aldehyde dehydrogenase [NAD+ ... |
M. tuberculosis | Rv3305c | OG5_127543 | Possible N-acyl-L-amino acid amidohydrolase AmiA1 (N-acyl-L-amino acid aminohydr ... |
M. tuberculosis | Rv1654 | OG5_130618 | Probable acetylglutamate kinase ArgB |
M. tuberculosis | Rv1652 | OG5_128464 | Probable N-acetyl-gamma-glutamyl-phoshate reductase ArgC |
M. tuberculosis | Rv1655 | OG5_126982 | Probable acetylornithine aminotransferase ArgD |
M. tuberculosis | Rv1658 | OG5_127707 | Probable argininosuccinate synthase ArgG |
M. tuberculosis | Rv2538c | OG5_127183 | 3-dehydroquinate synthase AroB |
M. tuberculosis | Rv2537c | OG5_132746 | 3-dehydroquinate dehydratase AroD (AROQ) (3-dehydroquinase) (type II dhqase) |
M. tuberculosis | Rv2178c | OG5_130802 | 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase AroG (DAHP synthetase, phen ... |
M. tuberculosis | Rv2539c | OG5_130547 | Shikimate kinase AroK (SK) |
M. tuberculosis | Rv3708c | OG5_128664 | Aspartate-semialdehyde dehydrogenase Asd (ASA dehydrogenase) (ASADH) (aspartic s ... |
M. tuberculosis | Rv1568 | OG5_128068 | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase BioA |
M. tuberculosis | Rv3392c | OG5_127897 | Cyclopropane-fatty-acyl-phospholipid synthase 1 CmaA1 (cyclopropane fatty acid s ... |
M. tuberculosis | Rv1092c | OG5_141174 | Probable pantothenate kinase CoaA (pantothenic acid kinase) |
M. tuberculosis | Rv1631 | OG5_127254 | Probable dephospho-CoA kinase CoaE (dephosphocoenzyme a kinase) |
M. tuberculosis | Rv2066 | OG5_135738 | Probable bifunctional protein, CobI-COBJ fusion protein: S-adenosyl-L-methionine ... |
M. tuberculosis | Rv2072c | OG5_135539 | Precorrin-6Y C(5,15)-methyltransferase (decarboxylating) CobL |
M. tuberculosis | Rv2849c | OG5_134037 | Probable cob(I)alamin adenosyltransferase CobO (corrinoid adenosyltransferase) ( ... |
M. tuberculosis | Rv2266 | OG5_132455 | Probable cytochrome P450 124 Cyp124 |
M. tuberculosis | Rv2268c | OG5_132455 | Probable cytochrome P450 128 Cyp128 |