Target list

Search results for query: T. cruzi ranked list of targets

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  • Score for genes in query #22 (enzyme): 30
  • Score for genes in query #29 (assayable): 15
  • Score for genes in query #25 (essentiality evidence in any specie): 20
  • Score for genes in query #27 (single copy gene): 20
  • Score for genes in query #28 (strucural model available): 15
  • Score for genes in query #24 (significant druggability): 30
  • Score for genes in query #23 (not in human): 40
  • Score for genes in query #26 (ortholog in T. brucei): 20

Convert this list of targets into a list of drugs:

Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.

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18619 records found | Showing page 2 of 745 (records 26-50) | Number of records to display | Find orthologs in

  Organism   Name     Ortholog group   Product Weight
T. cruzi   TcCLB.508647.200   OG5_127002   triosephosphate isomerase, putative 150
T. cruzi   TcCLB.510121.20   OG5_126743   hexokinase, putative 150
T. cruzi   TcCLB.503405.10   OG5_127569   glutamine synthetase, putative 150
T. cruzi   TcCLB.510053.60   OG5_127381   cytidine deaminase-like protein, putative 150
T. cruzi   TcCLB.509611.20   OG5_128367   peptidyl-prolyl cis-trans isomerase 150
T. cruzi   TcCLB.508175.370   OG5_127569   glutamine synthetase, putative 150
T. cruzi   TcCLB.510629.430   OG5_127549   prefoldin subunit, putative 145
T. cruzi   TcCLB.505763.19   OG5_127253   P-type H+-ATPase, putative 145
T. cruzi   TcCLB.510131.40   OG5_127435   haloacid dehalogenase-like hydrolase, putative 145
T. cruzi   TcCLB.503891.70   OG5_148060   ribonuclease HII, putative 145
T. cruzi   TcCLB.508777.90   OG5_127542   ATP-dependent DNA helicase, putative 145
T. cruzi   TcCLB.510287.60   OG5_148060   ribonuclease HII, putative 145
T. cruzi   TcCLB.506931.10   OG5_127435   haloacid dehalogenase-like hydrolase, putative 145
T. cruzi   TcCLB.510911.50   OG5_127334   glycine dehydrogenase [decarboxylating], putative 145
T. cruzi   TcCLB.510749.40   OG5_138353   ubiquitin hydrolase, putative 145
T. cruzi   TcCLB.511653.20   OG5_141243   dual-specificity protein phosphatase, putative 145
T. cruzi   TcCLB.510657.20   OG5_138353   ubiquitin hydrolase, putative 145
T. cruzi   TcCLB.503597.10   OG5_129171   homoserine kinase 145
T. cruzi   TcCLB.507011.260   OG5_130463   Tetrapyrrole (Corrin/Porphyrin) Methylases, putative 145
T. cruzi   TcCLB.506649.20   OG5_127253   P-type H+-ATPase, putative 145
T. cruzi   TcCLB.509163.80   OG5_127334   glycine dehydrogenase [decarboxylating], putative 145
T. cruzi   TcCLB.507639.50   OG5_128305   tRNA pseudouridine synthase A, putative 145
T. cruzi   TcCLB.511181.50   OG5_127023   mitochondrial processing peptidase, beta subunit, putative 145
T. cruzi   TcCLB.507011.120   OG5_146285   acyl transferase-like protein, putative 145
T. cruzi   TcCLB.506831.70   OG5_128638   glutamyl-tRNA synthetase, putative 145

Showing page 2 (records 26-50) of 745