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Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.
4804 records found | Showing page 1 of 193 (records 1-25) | Number of records to display | Find orthologs in
Organism | Name | Ortholog group | Product | Weight |
---|---|---|---|---|
P. falciparum | PF3D7_1439900 | OG5_127002 | triosephosphate isomerase | 466 |
P. falciparum | PF3D7_1029600 | OG5_127245 | adenosine deaminase | 451 |
P. falciparum | PF3D7_0322000 | OG5_126792 | peptidyl-prolyl cis-trans isomerase | 451 |
P. falciparum | PF3D7_0520900 | OG5_127233 | adenosylhomocysteinase | 451 |
P. falciparum | PF3D7_0922500 | OG5_126776 | phosphoglycerate kinase | 447 |
P. falciparum | PF3D7_0417200 | OG5_127385 | bifunctional dihydrofolate reductase-thymidylate synthase | 445 |
P. falciparum | PF3D7_1127100 | OG5_126992 | deoxyuridine 5'-triphosphate nucleotidohydrolase | 443 |
P. falciparum | PF3D7_1444800 | OG5_127143 | fructose-bisphosphate aldolase | 431 |
P. falciparum | PF3D7_1012400 | OG5_127374 | hypoxanthine-guanine phosphoribosyltransferase | 426 |
P. falciparum | PF3D7_1419800 | OG5_126785 | glutathione reductase | 423 |
P. falciparum | PF3D7_1405600 | OG5_126823 | ribonucleoside-diphosphate reductase small chain, putative | 420 |
P. falciparum | PF3D7_0615100 | OG5_130466 | enoyl-acyl carrier reductase | 420 |
P. falciparum | PF3D7_1414400 | OG5_126821 | serine/threonine protein phosphatase PP1 | 412 |
P. falciparum | PF3D7_1247400 | OG5_126727 | peptidyl-prolyl cis-trans isomerase FKBP35 | 412 |
P. falciparum | PF3D7_1115700 | OG5_126607 | cysteine proteinase falcipain 2a | 411 |
P. falciparum | PF3D7_1354500 | OG5_127011 | adenylosuccinate synthetase | 408 |
P. falciparum | PF3D7_1416500 | OG5_126857 | NADP-specific glutamate dehydrogenase | 400 |
P. falciparum | PF3D7_1434600 | OG5_127231 | methionine aminopeptidase 2 | 397 |
P. falciparum | PF3D7_1115600 | OG5_127452 | peptidyl-prolyl cis-trans isomerase | 393 |
P. falciparum | PF3D7_0312400 | OG5_126888 | glycogen synthase kinase 3 | 393 |
P. falciparum | PF3D7_0527300 | OG5_126721 | methionine aminopeptidase 1a, putative | 393 |
P. falciparum | PF3D7_1033100 | OG5_126750 | S-adenosylmethionine decarboxylase/ornithine decarboxylase | 391 |
P. falciparum | PF3D7_1324900 | OG5_126911 | L-lactate dehydrogenase | 391 |
P. falciparum | PF3D7_0623000 | OG5_128304 | chorismate synthase | 390 |
P. falciparum | PF3D7_1467300 | OG5_130462 | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | 386 |