Target list

Search results for query: Pfal rankings for 19 criteria -- reweightable!

You can Modify weights (moves query to your history allowing re-weight functionality) to match your needs

  • Score for genes in query #304 (Pfal late trophozoite 60-80): 4
  • Score for genes in query #297 (Pfal early ring 80-100): 8
  • Score for genes in query #291 (Pfal assayable): 30
  • Score for genes in query #294 (Pfal early schizont 80-100): 8
  • Score for genes in query #306 (Pfal late ring 80-100): 8
  • Score for genes in query #312 (Pfal merozoite 60-80): 4
  • Score for genes in query #311 (Pfal druggability > 0.6): 35
  • Score for genes in query #305 (Pfal not in humans): 25
  • Score for genes in query #315 (Pfal compound desirability > 0.3): 35
  • Score for genes in query #309 (Pfal no TM domains): 20
  • Score for genes in query #298 (Pfal late schizont 80-100): 8
  • Score for genes in query #310 (Pfal late trophozoite 80-100): 8
  • Score for genes in query #314 (Pfal late ring 60-80): 4
  • Score for genes in query #303 (Pfal PDB structures): 50
  • Score for genes in query #307 (Pfal genetic validation): 50
  • Score for genes in query #295 (Pfal early trophozoite 80-100): 8
  • Score for genes in query #300 (Pfal publications): 35
  • Score for genes in query #296 (Pfal early ring 60-80): 4
  • Score for genes in query #301 (Pfal enzymes): 100
  • Score for genes in query #292 (Pfal merozoite 80-100): 8
  • Score for genes in query #293 (Pfal late schizont 60-80): 4
  • Score for genes in query #299 (Pfal essential in at least one organism): 40
  • Score for genes in query #302 (Pfal structural models): 30
  • Score for genes in query #313 (Pfal less than 100 kDa): 20
  • Score for genes in query #316 (Pfal early schizont 60-80): 4
  • Score for genes in query #308 (Pfal early trophozoite 60-80): 4

Convert this list of targets into a list of drugs:

Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.

Retrieve:

4804 records found | Showing page 193 of 193 (records 4801-4804) | Number of records to display | Find orthologs in

  Organism   Name     Ortholog group   Product Weight
P. falciparum   PF3D7_1403700   OG5_126838   translocation associated membrane protein, putative 20
P. falciparum   PF3D7_1455900   OG5_129297   polyprenol reductase, putative 20
P. falciparum   PF3D7_0414300   OG5_130486   Rab5-interacting protein, putative 20
P. falciparum   PF3D7_0611000   OG5_128091   SNARE associated Golgi protein, putative 20

Showing page 193 (records 4801-4804) of 193