Target list

Search results for query: Pfal rankings for 19 criteria -- reweightable!

You can Modify weights (moves query to your history allowing re-weight functionality) to match your needs

  • Score for genes in query #304 (Pfal late trophozoite 60-80): 4
  • Score for genes in query #294 (Pfal early schizont 80-100): 8
  • Score for genes in query #312 (Pfal merozoite 60-80): 4
  • Score for genes in query #306 (Pfal late ring 80-100): 8
  • Score for genes in query #291 (Pfal assayable): 30
  • Score for genes in query #297 (Pfal early ring 80-100): 8
  • Score for genes in query #305 (Pfal not in humans): 25
  • Score for genes in query #311 (Pfal druggability > 0.6): 35
  • Score for genes in query #315 (Pfal compound desirability > 0.3): 35
  • Score for genes in query #309 (Pfal no TM domains): 20
  • Score for genes in query #303 (Pfal PDB structures): 50
  • Score for genes in query #307 (Pfal genetic validation): 50
  • Score for genes in query #298 (Pfal late schizont 80-100): 8
  • Score for genes in query #310 (Pfal late trophozoite 80-100): 8
  • Score for genes in query #314 (Pfal late ring 60-80): 4
  • Score for genes in query #295 (Pfal early trophozoite 80-100): 8
  • Score for genes in query #301 (Pfal enzymes): 100
  • Score for genes in query #300 (Pfal publications): 35
  • Score for genes in query #296 (Pfal early ring 60-80): 4
  • Score for genes in query #292 (Pfal merozoite 80-100): 8
  • Score for genes in query #299 (Pfal essential in at least one organism): 40
  • Score for genes in query #302 (Pfal structural models): 30
  • Score for genes in query #293 (Pfal late schizont 60-80): 4
  • Score for genes in query #308 (Pfal early trophozoite 60-80): 4
  • Score for genes in query #316 (Pfal early schizont 60-80): 4
  • Score for genes in query #313 (Pfal less than 100 kDa): 20

Convert this list of targets into a list of drugs:

Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.

Retrieve:

4804 records found | Showing page 2 of 193 (records 26-50) | Number of records to display | Find orthologs in

  Organism   Name     Ortholog group   Product Weight
P. falciparum   PF3D7_1015300   OG5_126721   methionine aminopeptidase 1b, putative 385
P. falciparum   PF3D7_0420200   OG5_130884   holo-[acyl-carrier-protein] synthase, putative 385
P. falciparum   PF3D7_0603300   OG5_127289   dihydroorotate dehydrogenase 385
P. falciparum   PF3D7_1462800   OG5_126628   glyceraldehyde-3-phosphate dehydrogenase 381
P. falciparum   PF3D7_0206700   OG5_130883   adenylosuccinate lyase 381
P. falciparum   PF3D7_1419300   OG5_128539   glutathione S-transferase 376
P. falciparum   PF3D7_0211400   OG5_129509   beta-ketoacyl-ACP synthase III 374
P. falciparum   PF3D7_1356900   OG5_126712   protein kinase 5 373
P. falciparum   PF3D7_0923800   OG5_126785   thioredoxin reductase 373
P. falciparum   PF3D7_0925700   OG5_126742   histone deacetylase 1 371
P. falciparum   PF3D7_0514600   OG5_127414   ribose-5-phosphate isomerase, putative 369
P. falciparum   PF3D7_1012600   OG5_127152   GMP synthase [glutamine-hydrolyzing] 367
P. falciparum   PF3D7_0510500   OG5_127702   topoisomerase I 367
P. falciparum   PF3D7_1008900   OG5_126762   adenylate kinase 366
P. falciparum   PF3D7_0513300   OG5_130516   purine nucleoside phosphorylase 366
P. falciparum   PF3D7_1401800   OG5_127835   choline kinase 364
P. falciparum   PF3D7_0406100   OG5_127061   V-type proton ATPase subunit B 363
P. falciparum   PF3D7_0920800   OG5_126887   inosine-5'-monophosphate dehydrogenase 363
P. falciparum   PF3D7_0810800   OG5_128803   hydroxymethyldihydropterin pyrophosphokinase-dihydropteroate synthase 362
P. falciparum   PF3D7_1128400   OG5_127590   geranylgeranyl pyrophosphate synthase, putative 362
P. falciparum   PF3D7_1115400   OG5_126607   cysteine proteinase falcipain 3 361
P. falciparum   PF3D7_1446200   OG5_127293   M17 leucyl aminopeptidase 361
P. falciparum   PF3D7_0932300   OG5_128020   M18 aspartyl aminopeptidase 357
P. falciparum   PF3D7_1343000   OG5_132295   phosphoethanolamine N-methyltransferase 356
P. falciparum   PF3D7_1407800   OG5_126885   plasmepsin IV 356

Showing page 2 (records 26-50) of 193