Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.
100 records found | Showing page 1 of 4 (records 1-25) | Number of records to display | Find orthologs in
| Organism | Name | Ortholog group | Product |
|---|---|---|---|
| M. tuberculosis | Rv1915 | OG5_129572 | Probable isocitrate lyase AceAa [first part] (isocitrase) (isocitratase) (Icl) |
| M. tuberculosis | Rv1916 | OG5_129572 | Probable isocitrate lyase AceAb [second part] (isocitrase) (isocitratase) (Icl) |
| M. tuberculosis | Rv2523c | OG5_130884 | holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pant ... |
| M. tuberculosis | Rv3252c | OG5_156889 | Probable transmembrane alkane 1-monooxygenase AlkB (alkane 1-hydroxylase) (lauri ... |
| M. tuberculosis | Rv3305c | OG5_127543 | Possible N-acyl-L-amino acid amidohydrolase AmiA1 (N-acyl-L-amino acid aminohydr ... |
| M. tuberculosis | Rv2538c | OG5_127183 | 3-dehydroquinate synthase AroB |
| M. tuberculosis | Rv2537c | OG5_132746 | 3-dehydroquinate dehydratase AroD (AROQ) (3-dehydroquinase) (type II dhqase) |
| M. tuberculosis | Rv2552c | OG5_128849 | Probable shikimate 5-dehydrogenase AroE (5-dehydroshikimate reductase) |
| M. tuberculosis | Rv2178c | OG5_130802 | 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase AroG (DAHP synthetase, phen ... |
| M. tuberculosis | Rv1311 | OG5_127404 | Probable ATP synthase epsilon chain AtpC |
| M. tuberculosis | Rv1306 | OG5_134191 | Probable ATP synthase B chain AtpF |
| M. tuberculosis | Rv2848c | OG5_132745 | Probable cobyrinic acid A,C-diamide synthase CobB |
| M. tuberculosis | Rv2066 | OG5_135738 | Probable bifunctional protein, CobI-COBJ fusion protein: S-adenosyl-L-methionine ... |
| M. tuberculosis | Rv2071c | OG5_135370 | Precorrin-3 methylase CobM (precorrin-4 C11-methyltransferase) |
| M. tuberculosis | Rv2849c | OG5_134037 | Probable cob(I)alamin adenosyltransferase CobO (corrinoid adenosyltransferase) ( ... |
| M. tuberculosis | Rv0255c | OG5_133997 | Probable cobyric acid synthase CobQ1 |
| M. tuberculosis | Rv1623c | OG5_130796 | Probable integral membrane cytochrome D ubiquinol oxidase (subunit I) CydA (cyto ... |
| M. tuberculosis | Rv1285 | OG5_137554 | Probable sulfate adenylyltransferase subunit 2 CysD |
| M. tuberculosis | Rv2335 | OG5_128713 | Probable serine acetyltransferase CysE (sat) |
| M. tuberculosis | Rv2392 | OG5_129962 | Probable 3'-phosphoadenosine 5'-phosphosulfate reductase CysH (PAPS reductase, t ... |
| M. tuberculosis | Rv2773c | OG5_131385 | Dihydrodipicolinate reductase DapB (DHPR) |
| M. tuberculosis | Rv2726c | OG5_130716 | Probable diaminopimelate epimerase DapF (DAP epimerase) |
| M. tuberculosis | Rv1547 | OG5_132143 | Probable DNA polymerase III (alpha chain) DnaE1 (DNA nucleotidyltransferase) |
| M. tuberculosis | Rv3370c | OG5_153489 | Probable DNA polymerase III (alpha chain) DnaE2 (DNA nucleotidyltransferase) |
| M. tuberculosis | Rv0002 | OG5_132148 | DNA polymerase III (beta chain) DnaN (DNA nucleotidyltransferase) |