Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.
100 records found | Showing page 2 of 4 (records 26-50) | Number of records to display | Find orthologs in
| Organism | Name | Ortholog group | Product |
|---|---|---|---|
| M. tuberculosis | Rv0533c | OG5_129509 | 3-oxoacyl-[acyl-carrier-protein] synthase III FabH (beta-ketoacyl-ACP synthase I ... |
| M. tuberculosis | Rv0363c | OG5_131639 | Probable fructose-bisphosphate aldolase Fba |
| M. tuberculosis | Rv3804c | OG5_210859 | Secreted antigen 85-a FbpA (mycolyl transferase 85A) (fibronectin-binding protei ... |
| M. tuberculosis | Rv3607c | OG5_133572 | Probable dihydroneopterin aldolase FolB (DHNA) |
| M. tuberculosis | Rv1554 | OG5_161648 | Probable fumarate reductase [membrane anchor subunit] FrdC (fumarate dehydrogena ... |
| M. tuberculosis | Rv1555 | OG5_161647 | Probable fumarate reductase [membrane anchor subunit] FrdD (fumarate dehydrogena ... |
| M. tuberculosis | Rv0727c | OG5_127052 | Possible L-fuculose phosphate aldolase FucA (L-fuculose-1-phosphate aldolase) |
| M. tuberculosis | Rv0993 | OG5_131936 | UTP--glucose-1-phosphate uridylyltransferase GalU (UDP-glucose pyrophosphorylase ... |
| M. tuberculosis | Rv1837c | OG5_159543 | Malate synthase G GlcB |
| M. tuberculosis | Rv3859c | OG5_126892 | Probable ferredoxin-dependent glutamate synthase [NADPH] (large subunit) GltB (L ... |
| M. tuberculosis | Rv3704c | OG5_139531 | Glutamate--cysteine ligase GshA (gamma-glutamylcysteine synthetase) (gamma-ECS) ... |
| M. tuberculosis | Rv0511 | OG5_128100 | Probable uroporphyrin-III C-methyltransferase HemD (uroporphyrinogen III methyla ... |
| M. tuberculosis | Rv1601 | OG5_129258 | Probable imidazole glycerol-phosphate dehydratase HisB |
| M. tuberculosis | Rv1600 | OG5_127656 | Probable histidinol-phosphate aminotransferase HisC1 |
| M. tuberculosis | Rv1605 | OG5_129302 | Probable cyclase HisF |
| M. tuberculosis | Rv1606 | OG5_131046 | Probable phosphoribosyl-AMP 1,6 cyclohydrolase HisI |
| M. tuberculosis | Rv0066c | OG5_126691 | Probable isocitrate dehydrogenase [NADP] Icd2 (oxalosuccinate decarboxylase) (ID ... |
| M. tuberculosis | Rv0467 | OG5_129572 | Isocitrate lyase Icl (isocitrase) (isocitratase) |
| M. tuberculosis | Rv3001c | OG5_129100 | Probable KETOL-acid reductoisomerase IlvC (acetohydroxy-acid isomeroreductase) ( ... |
| M. tuberculosis | Rv0189c | OG5_128618 | Probable dihydroxy-acid dehydratase IlvD (dad) |
| M. tuberculosis | Rv3002c | OG5_129345 | Probable acetolactate synthase (small subunit) IlvN (acetohydroxy-acid synthase) ... |
| M. tuberculosis | Rv0046c | OG5_139953 | myo-inositol-1-phosphate synthase Ino1 (inositol 1-phosphate synthetase) (D-gluc ... |
| M. tuberculosis | Rv2987c | OG5_130205 | Probable 3-isopropylmalate dehydratase (small subunit) LeuD (isopropylmalate iso ... |
| M. tuberculosis | Rv3382c | OG5_130373 | Probable LYTB-related protein LytB1 |
| M. tuberculosis | Rv1781c | OG5_133321 | Probable 4-alpha-glucanotransferase MalQ (amylomaltase) (disproportionating enzy ... |