Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.
136 records found | Showing page 1 of 6 (records 1-25) | Number of records to display | Find orthologs in
| Organism | Name | Ortholog group | Product |
|---|---|---|---|
| M. tuberculosis | Rv1915 | OG5_129572 | Probable isocitrate lyase AceAa [first part] (isocitrase) (isocitratase) (Icl) |
| M. tuberculosis | Rv1984c | OG5_136129 | Probable cutinase precursor CFP21 |
| M. tuberculosis | Rv1758 | OG5_136129 | Probable cutinase Cut1 |
| M. tuberculosis | Rv2276 | No group | Cytochrome P450 121 Cyp121 |
| M. tuberculosis | Rv3617 | OG5_129061 | Probable epoxide hydrolase EphA (epoxide hydratase) (arene-oxide hydratase) |
| M. tuberculosis | Rv3890c | No group | ESAT-6 like protein EsxC (ESAT-6 like protein 11) |
| M. tuberculosis | Rv0649 | No group | Possible malonyl CoA-acyl carrier protein transacylase FabD2 (MCT) |
| M. tuberculosis | Rv2002 | OG5_159475 | Possible 20-beta-hydroxysteroid dehydrogenase FabG3 (cortisone reductase) ((R)-2 ... |
| M. tuberculosis | Rv1912c | OG5_131137 | Possible oxidoreductase FadB5 |
| M. tuberculosis | Rv0404 | OG5_126609 | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthas ... |
| M. tuberculosis | Rv1878 | OG5_127086 | Probable glutamine synthetase GlnA3 (glutamine synthase) (GS-I) |
| M. tuberculosis | Rv2101 | OG5_128804 | Probable helicase HelZ |
| M. tuberculosis | Rv3084 | OG5_131762 | Probable acetyl-hydrolase/esterase LipR |
| M. tuberculosis | Rv1911c | OG5_130855 | Probable lipoprotein LppC |
| M. tuberculosis | Rv2270 | No group | Probable lipoprotein LppN |
| M. tuberculosis | Rv0962c | No group | Possible lipoprotein LprP |
| M. tuberculosis | Rv0405 | OG5_126633 | Probable membrane bound polyketide synthase Pks6 |
| M. tuberculosis | Rv2351c | OG5_131170 | Membrane-associated phospholipase C 1 PlcA (MTP40 antigen) |
| M. tuberculosis | Rv1755c | OG5_131170 | PROBABLE PHOSPHOLIPASE C 4 (FRAGMENT) PLCD |
| M. tuberculosis | Rv2353c | OG5_132376 | PPE family protein PPE39 |
| M. tuberculosis | Rv0388c | OG5_135481 | PPE family protein PPE9 |
| M. tuberculosis | Rv0071 | OG5_137048 | Possible maturase |
| M. tuberculosis | Rv0072 | OG5_153514 | Probable glutamine-transport transmembrane protein ABC transporter |
| M. tuberculosis | Rv0074 | OG5_133329 | Conserved protein |
| M. tuberculosis | Rv0143c | OG5_126837 | Probable conserved transmembrane protein |