Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.
504 records found | Showing page 1 of 21 (records 1-25) | Number of records to display | Find orthologs in
| Organism | Name | Ortholog group | Product |
|---|---|---|---|
| M. tuberculosis | Rv0002 | OG5_132148 | DNA polymerase III (beta chain) DnaN (DNA nucleotidyltransferase) |
| M. tuberculosis | Rv0005 | OG5_128755 | DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisome ... |
| M. tuberculosis | Rv0006 | OG5_129568 | DNA gyrase (subunit A) GyrA (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisome ... |
| M. tuberculosis | Rv0009 | OG5_128211 | Probable iron-regulated peptidyl-prolyl cis-trans isomerase A PpiA (PPIase A) (r ... |
| M. tuberculosis | Rv0011c | OG5_237531 | Probable conserved transmembrane protein |
| M. tuberculosis | Rv0014c | OG5_146588 | Transmembrane serine/threonine-protein kinase B PknB (protein kinase B) (STPK B) |
| M. tuberculosis | Rv0015c | OG5_155711 | Transmembrane serine/threonine-protein kinase A PknA (protein kinase A) (STPK A) |
| M. tuberculosis | Rv0016c | OG5_133524 | Probable penicillin-binding protein PbpA |
| M. tuberculosis | Rv0033 | No group | Probable acyl carrier protein AcpA (ACP) |
| M. tuberculosis | Rv0040c | OG5_237533 | Secreted proline rich protein Mtc28 (proline rich 28 kDa antigen) |
| M. tuberculosis | Rv0046c | OG5_139953 | myo-inositol-1-phosphate synthase Ino1 (inositol 1-phosphate synthetase) (D-gluc ... |
| M. tuberculosis | Rv0058 | OG5_131890 | Probable replicative DNA helicase DnaB |
| M. tuberculosis | Rv0060 | OG5_133608 | Conserved hypothetical protein |
| M. tuberculosis | Rv0062 | OG5_137267 | Possible cellulase CelA1 (endoglucanase) (endo-1,4-beta-glucanase) (FI-cmcase) ( ... |
| M. tuberculosis | Rv0066c | OG5_126691 | Probable isocitrate dehydrogenase [NADP] Icd2 (oxalosuccinate decarboxylase) (ID ... |
| M. tuberculosis | Rv0070c | OG5_126679 | Serine hydroxymethyltransferase GlyA2 (serine methylase 2) (SHMT 2) |
| M. tuberculosis | Rv0096 | OG5_237742 | PPE family protein PPE1 |
| M. tuberculosis | Rv0098 | OG5_237743 | Probable fatty acyl CoA thioesterase type III FcoT |
| M. tuberculosis | Rv0099 | OG5_163246 | Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-Co ... |
| M. tuberculosis | Rv0116c | OG5_237840 | Probable L,D-transpeptidase LdtA |
| M. tuberculosis | Rv0125 | OG5_171368 | Probable serine protease PepA (serine proteinase) (MTB32A) |
| M. tuberculosis | Rv0126 | OG5_126827 | Trehalose synthase TreS |
| M. tuberculosis | Rv0127 | OG5_239105 | Maltokinase Mak |
| M. tuberculosis | Rv0129c | OG5_237839 | Secreted antigen 85-C FbpC (85C) (antigen 85 complex C) (AG58C) (mycolyl transfe ... |
| M. tuberculosis | Rv0130 | OG5_142681 | Probable 3-hydroxyl-thioester dehydratase |