Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.
2253 records found | Showing page 2 of 91 (records 26-50) | Number of records to display | Find orthologs in
Organism | Name | Ortholog group | Product | Weight |
---|---|---|---|---|
M. tuberculosis | Rv1269c | OG5_239134 | Conserved probable secreted protein | 15 |
M. tuberculosis | Rv2050 | OG5_237694 | Conserved protein | 15 |
M. tuberculosis | Rv2822c | No group | Hypothetical protein | 15 |
M. tuberculosis | Rv3700c | OG5_127282 | Conserved hypothetical protein | 15 |
M. tuberculosis | Rv3785 | No group | Hypothetical protein | 15 |
M. tuberculosis | Rv0649 | No group | Possible malonyl CoA-acyl carrier protein transacylase FabD2 (MCT) | 14 |
M. tuberculosis | Rv1485 | OG5_127510 | Ferrochelatase HemZ (protoheme ferro-lyase) (heme synthetase) | 14 |
M. tuberculosis | Rv3116 | OG5_126966 | Probable molybdenum cofactor biosynthesis protein MoeB2 (MPT-synthase sulfurylas ... | 14 |
M. tuberculosis | Rv0484c | OG5_127267 | Probable short-chain type oxidoreductase | 14 |
M. tuberculosis | Rv0585c | OG5_187211 | Probable conserved integral membrane protein | 14 |
M. tuberculosis | Rv0597c | OG5_157133 | Conserved hypothetical protein | 14 |
M. tuberculosis | Rv1287 | OG5_132733 | Conserved hypothetical protein | 14 |
M. tuberculosis | Rv1404 | OG5_160441 | Probable transcriptional regulatory protein | 14 |
M. tuberculosis | Rv2104c | OG5_239154 | Possible antitoxin VapB37 | 14 |
M. tuberculosis | Rv2526 | No group | Possible antitoxin VapB17 | 14 |
M. tuberculosis | Rv2699c | OG5_237649 | Conserved hypothetical protein | 14 |
M. tuberculosis | Rv2901c | OG5_237710 | Conserved protein | 14 |
M. tuberculosis | Rv1689 | OG5_127413 | Probable tyrosyl-tRNA synthase TyrS (TYRRS) | 14 |
M. tuberculosis | Rv2874 | OG5_208929 | Possible integral membrane C-type cytochrome biogenesis protein DipZ | 13 |
M. tuberculosis | Rv1122 | OG5_127175 | Probable 6-phosphogluconate dehydrogenase, decarboxylating Gnd2 | 13 |
M. tuberculosis | Rv3469c | OG5_155516 | Probable 4-hydroxy-2-oxovalerate aldolase MhpE (HOA) | 13 |
M. tuberculosis | Rv2362c | OG5_143159 | Possible DNA repair protein RecO | 13 |
M. tuberculosis | Rv0705 | OG5_126687 | 30S ribosomal protein S19 RpsS | 13 |
M. tuberculosis | Rv0140 | OG5_144561 | Conserved protein | 13 |
M. tuberculosis | Rv1056 | OG5_144561 | Conserved protein | 13 |