Target list

Search results for query: Weighted ranking of Mtb targets based on gene essentiality and expression during persistence for PLOS-NTD

You can Modify weights (moves query to your history allowing re-weight functionality) to match your needs

  • Score for genes in query #9 (Mtb weighted list for gene attenuation score as in Murphy-Brown data): weighted list
  • Score for genes in query #5 (Mtu PDB structures): 20
  • Score for genes in query #2 (Hasan 2006 persistence, revised):
  • Score for genes in query #10 (Mtb weighted list for persistence expression score as in Murphy-Brown data): weighted list
  • Score for genes in query #8 (Mtu all proteins): 1

Convert this list of targets into a list of drugs:

Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.

Retrieve:

2253 records found | Showing page 91 of 91 (records 2251-2253) | Number of records to display | Find orthologs in

  Organism   Name     Ortholog group   Product Weight
M. tuberculosis   Rv2262c   OG5_133519   Conserved hypothetical protein -2062
M. tuberculosis   Rv0517   OG5_162561   Possible membrane acyltransferase -2067
M. tuberculosis   Rv0072   OG5_153514   Probable glutamine-transport transmembrane protein ABC transporter -2122

Showing page 91 (records 2251-2253) of 91