Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.
253 records found | Showing page 1 of 11 (records 1-25) | Number of records to display | Find orthologs in
| Organism | Name | Ortholog group | Product |
|---|---|---|---|
| P. falciparum | PF3D7_0110400 | OG5_128243 | DNA-directed RNA polymerase II subunit RPB9, putative |
| P. falciparum | PF3D7_0204500 | OG5_126737 | aspartate transaminase |
| P. falciparum | PF3D7_0204700 | OG5_127135 | hexose transporter |
| P. falciparum | PF3D7_0205500 | OG5_128606 | DNA-directed RNA polymerase II 16 kDa subunit, putative |
| P. falciparum | PF3D7_0206700 | OG5_130883 | adenylosuccinate lyase |
| P. falciparum | PF3D7_0209100 | OG5_137339 | phospholipase A2, putative |
| P. falciparum | PF3D7_0209300 | OG5_130616 | 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase |
| P. falciparum | PF3D7_0211400 | OG5_129509 | beta-ketoacyl-ACP synthase III |
| P. falciparum | PF3D7_0211700 | OG5_130251 | tyrosine kinase-like protein, putative |
| P. falciparum | PF3D7_0213400 | OG5_145294 | protein kinase 7 |
| P. falciparum | PF3D7_0215000 | OG5_129177 | acyl-CoA synthetase |
| P. falciparum | PF3D7_0215300 | OG5_136613 | acyl-CoA synthetase |
| P. falciparum | PF3D7_0215700 | OG5_126694 | DNA-directed RNA polymerase II subunit RPB2, putative |
| P. falciparum | PF3D7_0217500 | OG5_126600 | calcium-dependent protein kinase 1 |
| P. falciparum | PF3D7_0301000 | OG5_136613 | acyl-CoA synthetase |
| P. falciparum | PF3D7_0303300 | OG5_127345 | DNA-directed RNA polymerases I, II, and III subunit RPABC2, putative |
| P. falciparum | PF3D7_0307400 | OG5_127187 | ATP-dependent Clp protease proteolytic subunit |
| P. falciparum | PF3D7_0310100 | OG5_126600 | calcium-dependent protein kinase 3 |
| P. falciparum | PF3D7_0312400 | OG5_126888 | glycogen synthase kinase 3 |
| P. falciparum | PF3D7_0314400 | OG5_129276 | serine/threonine protein phosphatase 6, putative |
| P. falciparum | PF3D7_0317200 | OG5_147470 | cdc2-related protein kinase 4 |
| P. falciparum | PF3D7_0318200 | OG5_126637 | DNA-directed RNA polymerase II subunit RPB1 |
| P. falciparum | PF3D7_0318800 | OG5_162077 | triosephosphate isomerase, putative |
| P. falciparum | PF3D7_0320500 | OG5_127752 | nicotinamidase, putative |
| P. falciparum | PF3D7_0320800 | OG5_127804 | ATP-dependent RNA helicase DDX6 |