Target list

Search results for query: Weighted ranking of Pfa targets for PLOS-NTD

You can Modify weights (moves query to your history allowing re-weight functionality) to match your needs

  • Score for genes in query #87 (Mtb dindex >=0.6 (now searched on pfa)): 35
  • Score for genes in query #93 (Pfa in Pvi): 25
  • Score for genes in query #85 (Mtb any genetic validation (now searched on pfa)): 50
  • Score for genes in query #80 (Mtb mwt <100kDa (now searched on pfa)): 20
  • Score for genes in query #90 (Mtb all proteins (now searched on pfa)): 1
  • Score for genes in query #86 (Mtb any essentiality evidence (now searched on pfa)): 50
  • Score for genes in query #83 (Mtb modbase (now searched on pfa)): 30
  • Score for genes in query #88 (Mtb Compd desirability >0.3 (now searched on pfa)): 35
  • Score for genes in query #89 (Mtb assayable (now searched on pfa)): 35
  • Score for genes in query #82 (Mtb PDB (now searched on pfa)): 50
  • Score for genes in query #79 (Mtb Pubmed (now searched on pfa)): 35
  • Score for genes in query #84 (Mtb not in humans (now searched on pfa)): 25
  • Score for genes in query #81 (Mtb no TM domain (now searched on pfa)): 20
  • Score for genes in query #78 (Mtb enz (EC + func. Categ.) (now searched on pfa)): 100

Convert this list of targets into a list of drugs:

Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.

Retrieve:

4804 records found | Showing page 193 of 193 (records 4801-4804) | Number of records to display | Find orthologs in

  Organism   Name     Ortholog group   Product Weight
P. falciparum   PF3D7_1254300   OG5_132200   stevor 46
P. falciparum   PF3D7_1255000   OG5_126825   rifin 46
P. falciparum   PF3D7_0715100   OG5_129799   C-Myc-binding protein, putative 41
P. falciparum   PF3D7_1470000   OG5_130185   autophagy-related protein 12, putative 41

Showing page 193 (records 4801-4804) of 193