Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.
712 records found | Showing page 1 of 29 (records 1-25) | Number of records to display | Find orthologs in
| Organism | Name | Ortholog group | Product |
|---|---|---|---|
| M. tuberculosis | Rv0002 | OG5_132148 | DNA polymerase III (beta chain) DnaN (DNA nucleotidyltransferase) |
| M. tuberculosis | Rv0005 | OG5_128755 | DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisome ... |
| M. tuberculosis | Rv0006 | OG5_129568 | DNA gyrase (subunit A) GyrA (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisome ... |
| M. tuberculosis | Rv0009 | OG5_128211 | Probable iron-regulated peptidyl-prolyl cis-trans isomerase A PpiA (PPIase A) (r ... |
| M. tuberculosis | Rv0013 | OG5_128663 | Possible anthranilate synthase component II TrpG (glutamine amidotransferase) |
| M. tuberculosis | Rv0014c | OG5_146588 | Transmembrane serine/threonine-protein kinase B PknB (protein kinase B) (STPK B) |
| M. tuberculosis | Rv0015c | OG5_155711 | Transmembrane serine/threonine-protein kinase A PknA (protein kinase A) (STPK A) |
| M. tuberculosis | Rv0032 | OG5_126783 | Possible 8-amino-7-oxononanoate synthase BioF2 (AONS) (8-amino-7-ketopelargonate ... |
| M. tuberculosis | Rv0035 | No group | Probable fatty-acid-CoA ligase FadD34 (fatty-acid-CoA synthetase) (fatty-acid-Co ... |
| M. tuberculosis | Rv0044c | OG5_146706 | Possible oxidoreductase |
| M. tuberculosis | Rv0046c | OG5_139953 | myo-inositol-1-phosphate synthase Ino1 (inositol 1-phosphate synthetase) (D-gluc ... |
| M. tuberculosis | Rv0058 | OG5_131890 | Probable replicative DNA helicase DnaB |
| M. tuberculosis | Rv0062 | OG5_137267 | Possible cellulase CelA1 (endoglucanase) (endo-1,4-beta-glucanase) (FI-cmcase) ( ... |
| M. tuberculosis | Rv0066c | OG5_126691 | Probable isocitrate dehydrogenase [NADP] Icd2 (oxalosuccinate decarboxylase) (ID ... |
| M. tuberculosis | Rv0068 | OG5_126621 | Probable oxidoreductase |
| M. tuberculosis | Rv0069c | OG5_131061 | Probable L-serine dehydratase SdaA (L-serine deaminase) (SDH) (L-SD) |
| M. tuberculosis | Rv0070c | OG5_126679 | Serine hydroxymethyltransferase GlyA2 (serine methylase 2) (SHMT 2) |
| M. tuberculosis | Rv0075 | OG5_135774 | Probable aminotransferase |
| M. tuberculosis | Rv0077c | No group | Probable oxidoreductase |
| M. tuberculosis | Rv0082 | OG5_143851 | Probable oxidoreductase |
| M. tuberculosis | Rv0083 | OG5_139265 | Probable oxidoreductase |
| M. tuberculosis | Rv0084 | OG5_140388 | Possible formate hydrogenlyase HycD (FHL) |
| M. tuberculosis | Rv0085 | OG5_147565 | Possible hydrogenase HycP |
| M. tuberculosis | Rv0086 | OG5_134238 | Possible hydrogenase HycQ |
| M. tuberculosis | Rv0091 | OG5_130719 | Probable bifunctional MTA/SAH nucleosidase Mtn: 5'-methylthioadenosine nucleosid ... |