Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.
1688 records found | Showing page 1 of 68 (records 1-25) | Number of records to display | Find orthologs in
| Organism | Name | Ortholog group | Product |
|---|---|---|---|
| M. tuberculosis | Rv0001 | OG5_132291 | Chromosomal replication initiator protein DnaA |
| M. tuberculosis | Rv0002 | OG5_132148 | DNA polymerase III (beta chain) DnaN (DNA nucleotidyltransferase) |
| M. tuberculosis | Rv0003 | OG5_134856 | DNA replication and repair protein RecF (single-strand DNA binding protein) |
| M. tuberculosis | Rv0004 | OG5_166054 | Conserved hypothetical protein |
| M. tuberculosis | Rv0005 | OG5_128755 | DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisome ... |
| M. tuberculosis | Rv0006 | OG5_129568 | DNA gyrase (subunit A) GyrA (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisome ... |
| M. tuberculosis | Rv0007 | OG5_237529 | Possible conserved membrane protein |
| M. tuberculosis | Rv0009 | OG5_128211 | Probable iron-regulated peptidyl-prolyl cis-trans isomerase A PpiA (PPIase A) (r ... |
| M. tuberculosis | Rv0010c | OG5_237530 | Probable conserved membrane protein |
| M. tuberculosis | Rv0011c | OG5_237531 | Probable conserved transmembrane protein |
| M. tuberculosis | Rv0013 | OG5_128663 | Possible anthranilate synthase component II TrpG (glutamine amidotransferase) |
| M. tuberculosis | Rv0014c | OG5_146588 | Transmembrane serine/threonine-protein kinase B PknB (protein kinase B) (STPK B) |
| M. tuberculosis | Rv0015c | OG5_155711 | Transmembrane serine/threonine-protein kinase A PknA (protein kinase A) (STPK A) |
| M. tuberculosis | Rv0016c | OG5_133524 | Probable penicillin-binding protein PbpA |
| M. tuberculosis | Rv0017c | OG5_179437 | Probable cell division protein RodA |
| M. tuberculosis | Rv0018c | OG5_136773 | Phosphoserine/threonine phosphatase PstP |
| M. tuberculosis | Rv0019c | OG5_144332 | Conserved protein with FHA domain, FhaB |
| M. tuberculosis | Rv0020c | OG5_144358 | Conserved protein with FHA domain, FhaA |
| M. tuberculosis | Rv0032 | OG5_126783 | Possible 8-amino-7-oxononanoate synthase BioF2 (AONS) (8-amino-7-ketopelargonate ... |
| M. tuberculosis | Rv0038 | OG5_131289 | Conserved protein |
| M. tuberculosis | Rv0039c | OG5_237532 | Possible conserved transmembrane protein |
| M. tuberculosis | Rv0040c | OG5_237533 | Secreted proline rich protein Mtc28 (proline rich 28 kDa antigen) |
| M. tuberculosis | Rv0041 | OG5_127675 | Probable leucyl-tRNA synthetase LeuS (leucine--tRNA ligase) (LEURS) |
| M. tuberculosis | Rv0042c | OG5_130983 | Possible transcriptional regulatory protein (probably MarR-family) |
| M. tuberculosis | Rv0046c | OG5_139953 | myo-inositol-1-phosphate synthase Ino1 (inositol 1-phosphate synthetase) (D-gluc ... |