Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.
3198 records found | Showing page 2 of 128 (records 26-50) | Number of records to display | Find orthologs in
| Organism | Name | Ortholog group | Product |
|---|---|---|---|
| M. tuberculosis | Rv0038 | OG5_131289 | Conserved protein |
| M. tuberculosis | Rv0041 | OG5_127675 | Probable leucyl-tRNA synthetase LeuS (leucine--tRNA ligase) (LEURS) |
| M. tuberculosis | Rv0042c | OG5_130983 | Possible transcriptional regulatory protein (probably MarR-family) |
| M. tuberculosis | Rv0043c | OG5_178458 | Probable transcriptional regulatory protein (probably GntR-family) |
| M. tuberculosis | Rv0044c | OG5_146706 | Possible oxidoreductase |
| M. tuberculosis | Rv0045c | OG5_128173 | Possible hydrolase |
| M. tuberculosis | Rv0046c | OG5_139953 | myo-inositol-1-phosphate synthase Ino1 (inositol 1-phosphate synthetase) (D-gluc ... |
| M. tuberculosis | Rv0047c | OG5_178684 | Conserved protein |
| M. tuberculosis | Rv0049 | OG5_237841 | Conserved hypothetical protein |
| M. tuberculosis | Rv0050 | OG5_129763 | Probable bifunctional penicillin-binding protein 1A/1B PonA1 (murein polymerase) ... |
| M. tuberculosis | Rv0053 | OG5_131749 | 30S ribosomal protein S6 RpsF |
| M. tuberculosis | Rv0054 | OG5_127389 | Single-strand binding protein Ssb (helix-destabilizing protein) |
| M. tuberculosis | Rv0055 | OG5_128626 | 30S ribosomal protein S18-1 RpsR1 |
| M. tuberculosis | Rv0056 | OG5_130699 | 50S ribosomal protein L9 RplI |
| M. tuberculosis | Rv0057 | No group | Hypothetical protein |
| M. tuberculosis | Rv0058 | OG5_131890 | Probable replicative DNA helicase DnaB |
| M. tuberculosis | Rv0059 | OG5_239104 | Hypothetical protein |
| M. tuberculosis | Rv0060 | OG5_133608 | Conserved hypothetical protein |
| M. tuberculosis | Rv0061 | No group | HYPOTHETICAL PROTEIN |
| M. tuberculosis | Rv0061c | No group | Hypothetical protein |
| M. tuberculosis | Rv0063 | OG5_139417 | Possible oxidoreductase |
| M. tuberculosis | Rv0064A | No group | Possible antitoxin VapB1 |
| M. tuberculosis | Rv0065 | OG5_166544 | Possible toxin VapC1 |
| M. tuberculosis | Rv0066c | OG5_126691 | Probable isocitrate dehydrogenase [NADP] Icd2 (oxalosuccinate decarboxylase) (ID ... |
| M. tuberculosis | Rv0067c | OG5_178605 | Possible transcriptional regulatory protein (possibly TetR-family) |