Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.
1576 records found | Showing page 2 of 64 (records 26-50) | Number of records to display | Find orthologs in
| Organism | Name | Ortholog group | Product |
|---|---|---|---|
| M. tuberculosis | Rv0069c | OG5_131061 | Probable L-serine dehydratase SdaA (L-serine deaminase) (SDH) (L-SD) |
| M. tuberculosis | Rv0070c | OG5_126679 | Serine hydroxymethyltransferase GlyA2 (serine methylase 2) (SHMT 2) |
| M. tuberculosis | Rv0072 | OG5_153514 | Probable glutamine-transport transmembrane protein ABC transporter |
| M. tuberculosis | Rv0074 | OG5_133329 | Conserved protein |
| M. tuberculosis | Rv0075 | OG5_135774 | Probable aminotransferase |
| M. tuberculosis | Rv0077c | No group | Probable oxidoreductase |
| M. tuberculosis | Rv0080 | No group | Conserved hypothetical protein |
| M. tuberculosis | Rv0082 | OG5_143851 | Probable oxidoreductase |
| M. tuberculosis | Rv0083 | OG5_139265 | Probable oxidoreductase |
| M. tuberculosis | Rv0084 | OG5_140388 | Possible formate hydrogenlyase HycD (FHL) |
| M. tuberculosis | Rv0085 | OG5_147565 | Possible hydrogenase HycP |
| M. tuberculosis | Rv0091 | OG5_130719 | Probable bifunctional MTA/SAH nucleosidase Mtn: 5'-methylthioadenosine nucleosid ... |
| M. tuberculosis | Rv0092 | OG5_126855 | Cation transporter P-type ATPase a CtpA |
| M. tuberculosis | Rv0094c | OG5_151920 | Conserved hypothetical protein |
| M. tuberculosis | Rv0096 | OG5_237742 | PPE family protein PPE1 |
| M. tuberculosis | Rv0097 | OG5_129515 | Possible oxidoreductase |
| M. tuberculosis | Rv0099 | OG5_163246 | Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-Co ... |
| M. tuberculosis | Rv0102 | OG5_156768 | Probable conserved integral membrane protein |
| M. tuberculosis | Rv0110 | OG5_127224 | Probable conserved integral membrane protein |
| M. tuberculosis | Rv0112 | OG5_149659 | Possible GDP-mannose 4,6-dehydratase Gca (GDP-D-mannose dehydratase) |
| M. tuberculosis | Rv0114 | OG5_134734 | Possible D-alpha,beta-D-heptose-1,7-biphosphate phosphatase GmhB (D-glycero-D-ma ... |
| M. tuberculosis | Rv0116c | OG5_237840 | Probable L,D-transpeptidase LdtA |
| M. tuberculosis | Rv0124 | OG5_129879 | PE-PGRS family protein PE_PGRS2 |
| M. tuberculosis | Rv0126 | OG5_126827 | Trehalose synthase TreS |
| M. tuberculosis | Rv0127 | OG5_239105 | Maltokinase Mak |