Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.
213 records found | Showing page 2 of 9 (records 26-50) | Number of records to display | Find orthologs in
| Organism | Name | Ortholog group | Product |
|---|---|---|---|
| M. tuberculosis | Rv0462 | OG5_126968 | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydro ... |
| M. tuberculosis | Rv0467 | OG5_129572 | Isocitrate lyase Icl (isocitrase) (isocitratase) |
| M. tuberculosis | Rv0533c | OG5_129509 | 3-oxoacyl-[acyl-carrier-protein] synthase III FabH (beta-ketoacyl-ACP synthase I ... |
| M. tuberculosis | Rv0536 | OG5_130678 | Probable UDP-glucose 4-epimerase GalE3 (galactowaldenase) (UDP-galactose 4-epime ... |
| M. tuberculosis | Rv0548c | OG5_134385 | Naphthoate synthase MenB (dihydroxynaphthoic acid synthetase) (DHNA synthetase) |
| M. tuberculosis | Rv0620 | OG5_129789 | Probable galactokinase GalK (galactose kinase) |
| M. tuberculosis | Rv0632c | OG5_131454 | Probable enoyl-CoA hydratase EchA3 (enoyl hydrase) (unsaturated acyl-CoA hydrata ... |
| M. tuberculosis | Rv0649 | No group | Possible malonyl CoA-acyl carrier protein transacylase FabD2 (MCT) |
| M. tuberculosis | Rv0663 | OG5_197445 | Possible arylsulfatase AtsD (aryl-sulfate sulphohydrolase) (arylsulphatase) |
| M. tuberculosis | Rv0667 | OG5_130697 | DNA-directed RNA polymerase (beta chain) RpoB (transcriptase beta chain) (RNA po ... |
| M. tuberculosis | Rv0673 | OG5_211119 | Possible enoyl-CoA hydratase EchA4 (enoyl hydrase) (unsaturated acyl-CoA hydrata ... |
| M. tuberculosis | Rv0675 | OG5_133017 | Probable enoyl-CoA hydratase EchA5 (enoyl hydrase) (unsaturated acyl-CoA hydrata ... |
| M. tuberculosis | Rv0711 | OG5_126989 | Possible arylsulfatase AtsA (aryl-sulfate sulphohydrolase) (arylsulphatase) |
| M. tuberculosis | Rv0764c | OG5_129288 | Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lano ... |
| M. tuberculosis | Rv0770 | OG5_126809 | Probable dehydrogenase/reductase |
| M. tuberculosis | Rv0806c | OG5_135833 | Possible UDP-glucose-4-epimerase CpsY (galactowaldenase) (UDP-galactose-4-epimer ... |
| M. tuberculosis | Rv0815c | OG5_127129 | Probable thiosulfate sulfurtransferase CysA2 (rhodanese-like protein) (thiosulfa ... |
| M. tuberculosis | Rv0886 | OG5_217326 | Probable NADPH:adrenodoxin oxidoreductase FprB (adrenodoxin reductase) (AR) (fer ... |
| M. tuberculosis | Rv0889c | OG5_208928 | Probable citrate synthase II CitA |
| M. tuberculosis | Rv0905 | OG5_221959 | Possible enoyl-CoA hydratase EchA6 (enoyl hydrase) (unsaturated acyl-CoA hydrata ... |
| M. tuberculosis | Rv0946c | OG5_126980 | Probable glucose-6-phosphate isomerase Pgi (GPI) (phosphoglucose isomerase) (pho ... |
| M. tuberculosis | Rv0948c | OG5_237559 | Chorismate mutase |
| M. tuberculosis | Rv0971c | OG5_159313 | Probable enoyl-CoA hydratase EchA7 (enoyl hydrase) (unsaturated acyl-CoA hydrata ... |
| M. tuberculosis | Rv0993 | OG5_131936 | UTP--glucose-1-phosphate uridylyltransferase GalU (UDP-glucose pyrophosphorylase ... |
| M. tuberculosis | Rv1007c | OG5_127468 | Methionyl-tRNA synthetase MetS (MetRS) (methionine--tRNA ligase) |