Target list

Search results for query: Sma uploaded list of targets similar to known human targets (Berriman et al, 2009)

  • Query: Uploaded list
  • Unmatched identifiers: (Smp_026560) ; (Smp_040130) ; (Smp_048430) ; (Smp_053220) ; (Smp_069160) ; (Smp_090120) ; (Smp_090120) ; ("BLASTsearchresultsfromsearchesagainsttheDrugStoredatabase.Associateddrugsareclassifiedasfollows:[A]Directandclearevidencethatthisinteractionisprimarilyresponsibleforthetherapeuticactionofthedrug;[B]Directandclearevidencethatthisinteractionisonemechanismforthedrug,othertargets/mechanismsmayalsoexist.[C]Indirectorinferredevidenceoftheassociationofthedrug,targetandtherapeuticaction,althoughtheexactmechanismisstillspeculative.")

Convert this list of targets into a list of drugs:

Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.

Retrieve:

28 records found | Showing page 2 of 2 (records 26-28) | Number of records to display | Find orthologs in

  Organism   Name     Ortholog group   Product
S. mansoni   Smp_078040   OG5_126611   tubulin subunit beta
S. mansoni   Smp_040790   OG5_127452   cyclophilin B
S. mansoni   Smp_012930   OG5_126887   inosine-5-monophosphate dehydrogenase

Showing page 2 (records 26-28) of 2