Target list

Search results for query: Weighted ranking of B. malayi targets for PLOS-NTD

You can Modify weights (moves query to your history allowing re-weight functionality) to match your needs

  • Score for genes in query #316 (Bma assayable): 5
  • Score for genes in query #308 (Bma - embryonic lethal/arrest in Cel): 30
  • Score for genes in query #312 (Bma any essentiality): 5
  • Score for genes in query #310 (Bma - larval/adult lethal/arrest in Cel): 40
  • Score for genes in query #309 (Bma - growth defect in Cel): 20
  • Score for genes in query #314 (Bma any EC): 10
  • Score for genes in query #10 (Bma druggable precedence by similarity to starlite targets): 30
  • Score for genes in query #311 (Bma - morphology defect in Cel): 20
  • Score for genes in query #304 (Bma - sterile in Cel): 20
  • Score for genes in query #315 (Bma in PDB): 5
  • Score for genes in query #307 (Bma in Cel): 10
  • Score for genes in query #317 (Bma all proteins): 1
  • Score for genes in query #305 (Bma modbase): 2
  • Score for genes in query #306 (Bma pubmed): 2

Convert this list of targets into a list of drugs:

Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.

Retrieve:

11305 records found | Showing page 453 of 453 (records 11301-11305) | Number of records to display | Find orthologs in

  Organism   Name     Ortholog group   Product Weight
B. malayi   Bm1_09480     No group hypothetical protein 1
B. malayi   Bm1_05635   OG5_214523   hypothetical protein 1
B. malayi   Bm1_28180     No group hypothetical protein 1
B. malayi   Bm1_03215   OG5_145129   hypothetical protein 1
B. malayi   Bm1_13880   OG5_214626   hypothetical protein 1