Target list

Search results for query: PLoS NTD Query 11 (S. mansoni)

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  • Score for genes in query #268 (Sma all proteins): 1
  • Score for genes in query #265 ( expressed in egg stage (ESTs)): 3
  • Score for genes in query #260 (Sterility in C. elegans): 3
  • Score for genes in query #267 (expressed in any relevant stage (ESTs)): 10
  • Score for genes in query #257 (Growth Defect in C. elegans): 3
  • Score for genes in query #255 (Orthologs of D. melanogaster genes with mutant phenotype neurophysiological defect): 10
  • Score for genes in query #266 ( expressed in schistosomula stage (ESTs)): 3
  • Score for genes in query #262 (structural model available): 10
  • Score for genes in query #263 (druggable genes inferred by sequence simiarity): 10
  • Score for genes in query #273 (Sma uploaded list of targets similar to known human targets (Berriman et al, 2009)): 10
  • Score for genes in query #272 (Sma uploaded list of targets identified by STARlite search (Berriman et al, 2009)): 10
  • Score for genes in query #256 (Embryonic Lethal/Arrest in C. elegans): 10
  • Score for genes in query #254 (Orthologs of D. melanogaster genes with mutant phenotype lethal): 10
  • Score for genes in query #261 (any essentiality evidence): 3
  • Score for genes in query #264 (expressed in adult worm (ESTs)): 3
  • Score for genes in query #271 (Sma uploaded list of metabolic chokepoint enzymes (Berriman et al, 2009)): 10
  • Score for genes in query #270 (Sma in Cel): 10
  • Score for genes in query #258 (Larval/Adult Lethal/Arrest in C. elegans): 10
  • Score for genes in query #253 (Sma EC numbers - uploaded list): 10
  • Score for genes in query #259 (Morphology Defect in C. elegans): 3

Convert this list of targets into a list of drugs:

Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.

Retrieve:

12561 records found | Showing page 1 of 503 (records 1-25) | Number of records to display | Find orthologs in

  Organism   Name     Ortholog group   Product Weight
S. mansoni   Smp_015020   OG5_127003   Na+/K+ transporting ATPase subunit alpha 120
S. mansoni   Smp_059790.1   OG5_126720   transketolase 119
S. mansoni   Smp_059790.2   OG5_126720   transketolase 119
S. mansoni   Smp_040790   OG5_127452   cyclophilin B 113
S. mansoni   Smp_027920   OG5_126605   tubulin subunit alpha 112
S. mansoni   Smp_040970.1   OG5_126705   vacuolar proton atpases 112
S. mansoni   Smp_016780   OG5_126605   tubulin subunit alpha 109
S. mansoni   Smp_029390   OG5_127061   ATP synthase subunit beta vacuolar 106
S. mansoni   Smp_103140   OG5_126605   alpha tubulin 106
S. mansoni   Smp_142050   OG5_126781   serine/threonine protein kinase 103
S. mansoni   Smp_030730   OG5_126611   tubulin subunit beta 103
S. mansoni   Smp_071840   OG5_127175   6-phosphogluconate dehydrogenase 103
S. mansoni   Smp_106150   OG5_126835   aspartate carbamoyltransferase 103
S. mansoni   Smp_155270   OG5_190385   hydroxymethylglutaryl-CoA synthase 102
S. mansoni   Smp_090120.2   OG5_126605   alpha tubulin 102
S. mansoni   Smp_059340.1   OG5_131088   Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimula ... 102
S. mansoni   Smp_043670.1   OG5_126758   6-phosphofructokinase 102
S. mansoni   Smp_059340.2   OG5_131088   Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimula ... 102
S. mansoni   Smp_090120.1   OG5_126605   alpha tubulin 102
S. mansoni   Smp_035760   OG5_126611   tubulin subunit beta 100
S. mansoni   Smp_079960   OG5_126611   tubulin subunit beta 100
S. mansoni   Smp_079970   OG5_126611   tubulin subunit beta 100
S. mansoni   Smp_078040   OG5_126611   tubulin subunit beta 100
S. mansoni   Smp_138590   OG5_127955   hydroxymethylglutaryl-CoA reductase (NADPH) 99
S. mansoni   Smp_034490   OG5_127762   proteasome catalytic subunit 1 (T01 family) 99

Showing page 1 (records 1-25) of 503