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Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.
4804 records found | Showing page 1 of 193 (records 1-25) | Number of records to display | Find orthologs in
Organism | Name | Ortholog group | Product | Weight |
---|---|---|---|---|
P. falciparum | PF3D7_0417200 | OG5_127385 | bifunctional dihydrofolate reductase-thymidylate synthase | 486 |
P. falciparum | PF3D7_0615100 | OG5_130466 | enoyl-acyl carrier reductase | 461 |
P. falciparum | PF3D7_1439900 | OG5_127002 | triosephosphate isomerase | 451 |
P. falciparum | PF3D7_1029600 | OG5_127245 | adenosine deaminase | 436 |
P. falciparum | PF3D7_1127100 | OG5_126992 | deoxyuridine 5'-triphosphate nucleotidohydrolase | 436 |
P. falciparum | PF3D7_1419800 | OG5_126785 | glutathione reductase | 436 |
P. falciparum | PF3D7_0322000 | OG5_126792 | peptidyl-prolyl cis-trans isomerase | 436 |
P. falciparum | PF3D7_0520900 | OG5_127233 | adenosylhomocysteinase | 436 |
P. falciparum | PF3D7_0922500 | OG5_126776 | phosphoglycerate kinase | 436 |
P. falciparum | PF3D7_0420200 | OG5_130884 | holo-[acyl-carrier-protein] synthase, putative | 426 |
P. falciparum | PF3D7_0623000 | OG5_128304 | chorismate synthase | 426 |
P. falciparum | PF3D7_1405600 | OG5_126823 | ribonucleoside-diphosphate reductase small chain, putative | 416 |
P. falciparum | PF3D7_1444800 | OG5_127143 | fructose-bisphosphate aldolase | 416 |
P. falciparum | PF3D7_0603300 | OG5_127289 | dihydroorotate dehydrogenase | 416 |
P. falciparum | PF3D7_1467300 | OG5_130462 | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | 411 |
P. falciparum | PF3D7_0211400 | OG5_129509 | beta-ketoacyl-ACP synthase III | 411 |
P. falciparum | PF3D7_1012400 | OG5_127374 | hypoxanthine-guanine phosphoribosyltransferase | 401 |
P. falciparum | PF3D7_1354500 | OG5_127011 | adenylosuccinate synthetase | 401 |
P. falciparum | PF3D7_1414400 | OG5_126821 | serine/threonine protein phosphatase PP1 | 401 |
P. falciparum | PF3D7_1416500 | OG5_126857 | NADP-specific glutamate dehydrogenase | 401 |
P. falciparum | PF3D7_1247400 | OG5_126727 | peptidyl-prolyl cis-trans isomerase FKBP35 | 401 |
P. falciparum | PF3D7_0810800 | OG5_128803 | hydroxymethyldihydropterin pyrophosphokinase-dihydropteroate synthase | 391 |
P. falciparum | PF3D7_1015300 | OG5_126721 | methionine aminopeptidase 1b, putative | 386 |
P. falciparum | PF3D7_1115600 | OG5_127452 | peptidyl-prolyl cis-trans isomerase | 386 |
P. falciparum | PF3D7_1434600 | OG5_127231 | methionine aminopeptidase 2 | 386 |