Target list

Search results for query: PLoS NTD Query 9 (M. tuberculosis persistence)

You can Modify weights (moves query to your history allowing re-weight functionality) to match your needs

  • Score for genes in query #508 (Murphy & Brown scores): weighted list
  • Score for genes in query #507 (Mtu genes w/ PDB structures): 5
  • Score for genes in query #509 (Hasan et al. persistence scores): weighted list

Convert this list of targets into a list of drugs:

Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.

Retrieve:

2253 records found | Showing page 2 of 91 (records 26-50) | Number of records to display | Find orthologs in

  Organism   Name     Ortholog group   Product Weight
M. tuberculosis   Rv2115c   OG5_237684   Mycobacterial proteasome ATPase Mpa 549
M. tuberculosis   Rv2710   OG5_237645   RNA polymerase sigma factor SigB 545
M. tuberculosis   Rv2496c   OG5_128323   Probable branched-chain keto acid dehydrogenase E1 component, beta subunit BkdB 536
M. tuberculosis   Rv2031c   OG5_126935   Heat shock protein HspX (alpha-crystallin homolog) (14 kDa antigen) (HSP16.3) 532
M. tuberculosis   Rv1738   OG5_239144   Conserved protein 530
M. tuberculosis   Rv0116c   OG5_237840   Probable L,D-transpeptidase LdtA 529
M. tuberculosis   Rv0569   OG5_239117   Conserved protein 523
M. tuberculosis   Rv0190   OG5_136234   Conserved protein 521
M. tuberculosis   Rv3132c   OG5_153508   Two component sensor histidine kinase DevS 519
M. tuberculosis   Rv1734c     No group Conserved hypothetical protein 508
M. tuberculosis   Rv0810c   OG5_237775   Conserved hypothetical protein 505
M. tuberculosis   Rv1286   OG5_168022   Probable bifunctional enzyme CysN/CysC: sulfate adenyltransferase (subunit 1) + ... 492
M. tuberculosis   Rv2694c     No group Conserved protein 490
M. tuberculosis   Rv1894c   OG5_141344   Conserved hypothetical protein 470
M. tuberculosis   Rv0872c   OG5_129879   PE-PGRS family protein PE_PGRS15 452
M. tuberculosis   Rv0467   OG5_129572   Isocitrate lyase Icl (isocitrase) (isocitratase) 450
M. tuberculosis   Rv1405c   OG5_176030   Putative methyltransferase 449
M. tuberculosis   Rv3371   OG5_133846   Possible triacylglycerol synthase (diacylglycerol acyltransferase) 446
M. tuberculosis   Rv2029c   OG5_132575   6-phosphofructokinase PfkB (phosphohexokinase) (phosphofructokinase) 443
M. tuberculosis   Rv0197   OG5_175709   Possible oxidoreductase 443
M. tuberculosis   Rv1956   OG5_160559   Possible antitoxin HigA 443
M. tuberculosis   Rv2358   OG5_155588   Probable transcriptional regulatory protein SmtB (probably ArsR-family) 443
M. tuberculosis   Rv2036   OG5_239152   Conserved hypothetical protein 441
M. tuberculosis   Rv2500c   OG5_128729   Possible acyl-CoA dehydrogenase FadE19 (MMGC) 439
M. tuberculosis   Rv2466c   OG5_237696   Conserved protein 435

Showing page 2 (records 26-50) of 91