Target list

Search results for query: PLoS NTD Query 6 (T. brucei glycolysis)

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  • Score for genes in query #301 (uploaded weighted list of enzymes influencing glycolytic flux in Tbr): 0
  • Score for genes in query #293 (Tbr all proteins): 1
  • Score for genes in query #297 (Tbr Dindex >=0.4): 20
  • Score for genes in query #295 (Tbr PDB structure): 20
  • Score for genes in query #300 (Tbr Glycolysis from KEGG): 1000
  • Score for genes in query #298 (Tbr Compound desirability > 0.2): 10
  • Score for genes in query #299 (Tbr assayable): 20
  • Score for genes in query #294 (Tbr in Pubmed): 20
  • Score for genes in query #296 (Tbr modbase structures): 10

Convert this list of targets into a list of drugs:

Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.

Retrieve:

8299 records found | Showing page 2 of 332 (records 26-50) | Number of records to display | Find orthologs in

  Organism   Name     Ortholog group   Product Weight
T. brucei   Tb927.10.7570   OG5_128029   dihydrolipoamide acetyltransferase E2 subunit, putative 1011
T. brucei   Tb927.3.2030   OG5_127552   acylphosphatase, putative 1011
T. brucei   Tb927.3.1790   OG5_127524   pyruvate dehydrogenase E1 beta subunit, putative 1011
T. brucei   Tb927.10.2350   OG5_145729   pyruvate dehydrogenase complex E3 binding protein, putative 1011
T. brucei   Tb927.6.4210   OG5_131364   aldehyde dehydrogenase, putative 1011
T. brucei   Tb427.10.4330     No group 2-oxoisovalerate dehydrogenase beta subunit, mitochondrial precursor, putative 1001
T. brucei   Tb927.7.3360   OG5_127590   farnesyl pyrophosphate synthase 101
T. brucei   Tb927.11.13730   OG5_126750   ornithine decarboxylase 101
T. brucei   Tb927.10.14070   OG5_128252   mevalonate diphosphate decarboxylase 81
T. brucei   Tb927.4.4590   OG5_157978   AGC family serine/threonine kinase, putative 81
T. brucei   Tb11.v5.0718   OG5_126888   protein kinase, putative 81
T. brucei   Tb927.10.10390   OG5_126785   trypanothione reductase 81
T. brucei   Tb927.6.4410   OG5_128279   S-adenosylmethionine decarboxylase 81
T. brucei   Tb927.10.880   OG5_129576   thymidine kinase 81
T. brucei   Tb927.4.3810   OG5_126694   DNA-directed RNA polymerase II subunit 2, putative 81
T. brucei   Tb927.10.13560   OG5_128252   mevalonate-diphosphate decarboxylase 81
T. brucei   Tb927.10.4990   OG5_126712   cdc2-related kinase 3 81
T. brucei   Tb927.11.9590   OG5_127233   S-adenosylhomocysteine hydrolase, putative 81
T. brucei   Tb927.8.2000   OG5_126792   cyclophilin, putative 81
T. brucei   Tb927.11.14780   OG5_127555   phosphomannose isomerase 81
T. brucei   Tb927.10.1070   OG5_126712   cdc2-related kinase 1 81
T. brucei   Tb927.5.3830   OG5_127289   dihydroorotate dehydrogenase (fumarate) 81
T. brucei   Tb927.7.4770   OG5_127452   cyclophilin-type peptidyl-prolyl cis-trans isomerase, putative 81
T. brucei   Tb927.10.12370   OG5_128698   gamma-glutamylcysteine synthetase 81
T. brucei   Tb927.10.13630   OG5_126880   glucosidase, putative 81

Showing page 2 (records 26-50) of 332