Target list

Search results for query: PLoS NTD Query 11 (S. mansoni)

You can Modify weights (moves query to your history allowing re-weight functionality) to match your needs

  • Score for genes in query #272 (Sma uploaded list of targets identified by STARlite search (Berriman et al, 2009)): 10
  • Score for genes in query #267 (expressed in any relevant stage (ESTs)): 10
  • Score for genes in query #263 (druggable genes inferred by sequence simiarity): 10
  • Score for genes in query #256 (Embryonic Lethal/Arrest in C. elegans): 10
  • Score for genes in query #257 (Growth Defect in C. elegans): 3
  • Score for genes in query #273 (Sma uploaded list of targets similar to known human targets (Berriman et al, 2009)): 10
  • Score for genes in query #262 (structural model available): 10
  • Score for genes in query #255 (Orthologs of D. melanogaster genes with mutant phenotype neurophysiological defect): 10
  • Score for genes in query #259 (Morphology Defect in C. elegans): 3
  • Score for genes in query #271 (Sma uploaded list of metabolic chokepoint enzymes (Berriman et al, 2009)): 10
  • Score for genes in query #260 (Sterility in C. elegans): 3
  • Score for genes in query #264 (expressed in adult worm (ESTs)): 3
  • Score for genes in query #253 (Sma EC numbers - uploaded list): 10
  • Score for genes in query #266 ( expressed in schistosomula stage (ESTs)): 3
  • Score for genes in query #261 (any essentiality evidence): 3
  • Score for genes in query #270 (Sma in Cel): 10
  • Score for genes in query #254 (Orthologs of D. melanogaster genes with mutant phenotype lethal): 10
  • Score for genes in query #268 (Sma all proteins): 1
  • Score for genes in query #265 ( expressed in egg stage (ESTs)): 3
  • Score for genes in query #258 (Larval/Adult Lethal/Arrest in C. elegans): 10

Convert this list of targets into a list of drugs:

Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.

Retrieve:

12561 records found | Showing page 2 of 503 (records 26-50) | Number of records to display | Find orthologs in

  Organism   Name     Ortholog group   Product Weight
S. mansoni   Smp_096020.2   OG5_130931   adenosylhomocysteinase 99
S. mansoni   Smp_028440.1   OG5_127233   adenosylhomocysteinase 99
S. mansoni   Smp_097590   OG5_126723   valine-tRNA ligase 99
S. mansoni   Smp_096020.1   OG5_130931   adenosylhomocysteinase 99
S. mansoni   Smp_165490   OG5_127141   protein phsophatase-2a 99
S. mansoni   Smp_028990.1   OG5_126821   protein phosphatase-1 99
S. mansoni   Smp_096020.3   OG5_130931   adenosylhomocysteinase 99
S. mansoni   Smp_192110   OG5_126611   tubulin subunit beta 97
S. mansoni   Smp_004810.3   OG5_126821   protein phosphatase type 1 96
S. mansoni   Smp_025010   OG5_126846   casein kinase II beta subunit 96
S. mansoni   Smp_025800   OG5_127834   proteasome subunit beta 1 (T01 family) 96
S. mansoni   Smp_147050   OG5_127237   ATP synthase alpha subunit vacuolar 96
S. mansoni   Smp_079760.1   OG5_132787   protein kinase 96
S. mansoni   Smp_052810   OG5_127121   glucose-6-phosphate 1-dehydrogenase 96
S. mansoni   Smp_136710.1   OG5_126674   calcium-transporting atpase sarcoplasmic/endoplasmic reticulum type (calcium pum ... 96
S. mansoni   Smp_055990   OG5_127011   adenylosuccinate synthetase 96
S. mansoni   Smp_007260.1   OG5_126674   ATPase 96
S. mansoni   Smp_121420   OG5_127597   N-myristoyltransferase 96
S. mansoni   Smp_042590.1   OG5_128019   NADH-ubiquinone oxidoreductase 96
S. mansoni   Smp_129050   OG5_126660   dynamin 96
S. mansoni   Smp_018260   OG5_129425   glycogen synthase 96
S. mansoni   Smp_170730   OG5_127884   proteasome subunit alpha 1 (T01 family) 96
S. mansoni   Smp_009030   OG5_126839   ribonucleoside-diphosphate reductase alpha subunit 96
S. mansoni   Smp_136710.2   OG5_126674   calcium-transporting atpase sarcoplasmic/endoplasmic reticulum type (calcium pum ... 96
S. mansoni   Smp_096270   OG5_126723   valine-tRNA ligase 96

Showing page 2 (records 26-50) of 503