Target list

Search results for query: PLoS NTD Query 2 (L. major)

You can Modify weights (moves query to your history allowing re-weight functionality) to match your needs

  • Score for genes in query #107 (Mtb all proteins (now searched on lma)): 1
  • Score for genes in query #98 (Mtb no TM domain (now searched on lma)): 20
  • Score for genes in query #104 (Mtb dindex >=0.6 (now searched on lma)): 35
  • Score for genes in query #110 (Lma in Tbr and Tcr): 25
  • Score for genes in query #102 (Mtb any genetic validation (now searched on lma)): 50
  • Score for genes in query #106 (Mtb assayable (now searched on lma)): 35
  • Score for genes in query #101 (Mtb not in humans (now searched on lma)): 25
  • Score for genes in query #96 (Mtb Pubmed (now searched on lma)): 35
  • Score for genes in query #100 (Mtb modbase (now searched on lma)): 30
  • Score for genes in query #97 (Mtb mwt <100kDa (now searched on lma)): 20
  • Score for genes in query #95 (Mtb enz (EC + func. Categ.) (now searched on lma)): 100
  • Score for genes in query #99 (Mtb PDB (now searched on lma)): 50
  • Score for genes in query #105 (Mtb Compd desirability >0.3 (now searched on lma)): 35

Convert this list of targets into a list of drugs:

Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.

Retrieve:

8243 records found | Showing page 2 of 330 (records 26-50) | Number of records to display | Find orthologs in

  Organism   Name     Ortholog group   Product Weight
L. major   LmjF.36.2380   OG5_129172   sterol 24-c-methyltransferase, putative 326
L. major   LmjF.32.1820   OG5_126676   iron superoxide dismutase, putative 316
L. major   LmjF.36.1260   OG5_127143   fructose-1,6-bisphosphate aldolase 316
L. major   LmjF.28.2280   OG5_127113   DNA topoisomerase ii 316
L. major   LmjF.20.0100   OG5_126776   phosphoglycerate kinase C, glycosomal 316
L. major   LmjF.33.1690   OG5_127429   DNA polymerase delta catalytic subunit, putative 316
L. major   LmjF.18.0990   OG5_128034   UDP-glucose pyrophosphorylase 316
L. major   LmjF.18.0090   OG5_126880   alpha glucosidase II subunit, putative 316
L. major   LmjF.35.0030   OG5_126685   pyruvate kinase 316
L. major   LmjF.32.1830   OG5_126676   iron superoxide dismutase, putative 316
L. major   LmjF.26.0140   OG5_127379   adenine phosphoribosyltransferase 316
L. major   LmjF.21.1080   OG5_126712   cell division protein kinase 2,cdc2-related kinase 316
L. major   LmjF.05.0970   OG5_127129   3-mercaptopyruvate sulfurtransferase 316
L. major   LmjF.12.0530   OG5_126980   glucose-6-phosphate isomerase 316
L. major   LmjF.35.0020   OG5_126685   pyruvate kinase 316
L. major   LmjF.16.1540   OG5_128177   DNA polymerase I alpha catalytic subunit, putative 316
L. major   LmjF.10.0465   OG5_126749   GP63, leishmanolysin 311
L. major   LmjF.10.0460   OG5_126749   GP63, leishmanolysin 311
L. major   LmjF.10.0480   OG5_126749   GP63, leishmanolysin 311
L. major   LmjF.34.0150   OG5_126911   malate dehydrogenase, putative 311
L. major   LmjF.12.0280   OG5_126750   ornithine decarboxylase, putative 311
L. major   LmjF.10.0470   OG5_126749   GP63, leishmanolysin 311
L. major   LmjF.34.4330   OG5_131023   quinonoid dihydropteridine reductase 311
L. major   LmjF.04.0060   OG5_145769   DNA topoisomerase type IB small subunit 306
L. major   LmjF.31.1220   OG5_128905   vacuolar-type proton translocating pyrophosphatase 1, putative 306

Showing page 2 (records 26-50) of 330