Target list

Search results for query: PLoS NTD Query 5 (M. tuberculosis)

You can Modify weights (moves query to your history allowing re-weight functionality) to match your needs

  • Score for genes in query #60 (Mtb enz (EC + func. Categ.)): 100
  • Score for genes in query #63 (Mtb no TM domain): 20
  • Score for genes in query #66 (Mtb not in humans): 25
  • Score for genes in query #61 (Mtb Pubmed): 35
  • Score for genes in query #67 (Mtb in Mle): 25
  • Score for genes in query #69 (Mtb any essentiality evidence): 50
  • Score for genes in query #71 (Mtb Compd desirability >0.3): 35
  • Score for genes in query #62 (Mtb mwt <100kDa): 20
  • Score for genes in query #72 (Mtb assayable): 35
  • Score for genes in query #74 (Mtb all proteins): 1
  • Score for genes in query #65 (Mtb modbase): 30
  • Score for genes in query #64 (Mtb PDB): 50
  • Score for genes in query #68 (Mtb any genetic validation): 50
  • Score for genes in query #70 (Mtb dindex >=0.6): 35

Convert this list of targets into a list of drugs:

Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.

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2253 records found | Showing page 91 of 91 (records 2251-2253) | Number of records to display | Find orthologs in

  Organism   Name     Ortholog group   Product Weight
M. tuberculosis   Rv3479   OG5_216102   Possible transmembrane protein 26
M. tuberculosis   Rv2307c   OG5_128284   Conserved hypothetical protein 21
M. tuberculosis   Rv3238c   OG5_133700   Probable conserved integral membrane protein 21