Target list

Search results for query: PLoS NTD query (L. major)

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  • Score for genes in query #526 (L. major no transmembrane domains): 20
  • Score for genes in query #525 (L. major MW < 100 kD): 20
  • Score for genes in query #531 (L. major genetic validation): 50
  • Score for genes in query #534 (L. major assayability precedent): 35
  • Score for genes in query #527 (L. major PDB structures): 50
  • Score for genes in query #530 (L. major conserved in TriTryps): 25
  • Score for genes in query #522 (all L. major proteins): 1
  • Score for genes in query #528 (L. major ModBase models): 30
  • Score for genes in query #524 (L. major PubMed publications): 35
  • Score for genes in query #523 (L. major enzymes): 100
  • Score for genes in query #529 (L. major not in humans): 25
  • Score for genes in query #532 (L. major druggability >=0.6): 35

Convert this list of targets into a list of drugs:

Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.

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8243 records found | Showing page 2 of 330 (records 26-50) | Number of records to display | Find orthologs in

  Organism   Name     Ortholog group   Product Weight
L. major   LmjF.26.0140   OG5_127379   adenine phosphoribosyltransferase 316
L. major   LmjF.05.0970   OG5_127129   3-mercaptopyruvate sulfurtransferase 316
L. major   LmjF.12.0530   OG5_126980   glucose-6-phosphate isomerase 316
L. major   LmjF.35.0020   OG5_126685   pyruvate kinase 316
L. major   LmjF.10.0465   OG5_126749   GP63, leishmanolysin 311
L. major   LmjF.10.0460   OG5_126749   GP63, leishmanolysin 311
L. major   LmjF.10.0480   OG5_126749   GP63, leishmanolysin 311
L. major   LmjF.10.0470   OG5_126749   GP63, leishmanolysin 311
L. major   LmjF.34.2000   OG5_150045   pyroglutamyl-peptidase I (C15 family) 306
L. major   LmjF.04.0060   OG5_145769   DNA topoisomerase type IB small subunit 306
L. major   LmjF.31.1220   OG5_128905   vacuolar-type proton translocating pyrophosphatase 1, putative 306
L. major   LmjF.20.1310   OG5_138266   small myristoylated protein-1 306
L. major   LmjF.04.1160   OG5_127400   301
L. major   LmjF.30.3520   OG5_126734   S-adenosylmethionine synthetase 301
L. major   LmjF.28.2860   OG5_127410   cytosolic malate dehydrogenase 301
L. major   LmjF.34.1260   OG5_127218   mitochondrial DNA polymerase I protein A, putative 301
L. major   LmjF.18.1080   OG5_126748   protein kinase A catalytic subunit 301
L. major   LmjF.28.0690   OG5_126821   serine/threonine protein phosphatase catalytic subunit, putative 301
L. major   LmjF.10.0890   OG5_128118   FKBP-type peptidyl-prolyl cis-trans isomerase, putative 301
L. major   LmjF.08.1070   OG5_126607   cathepsin L-like protease 301
L. major   LmjF.23.0950   OG5_127293   cytosolic leucyl aminopeptidase,metallo-peptidase, Clan MF, Family M17 301
L. major   LmjF.33.1630   OG5_126792   cyclophilin 4, putative 301
L. major   LmjF.07.1030   OG5_128367   peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 301
L. major   LmjF.08.1050   OG5_126607   cathepsin L-like protease 301
L. major   LmjF.19.1530   OG5_126727   peptidylprolyl isomerase-like protein 301

Showing page 2 (records 26-50) of 330