Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.
2240 records found | Showing page 2 of 90 (records 26-50) | Number of records to display | Find orthologs in
Organism | Name | Ortholog group | Product | Weight |
---|---|---|---|---|
M. tuberculosis | Rv0569 | OG5_239117 | Conserved protein | 398 |
M. tuberculosis | Rv1738 | OG5_239144 | Conserved protein | 397 |
M. tuberculosis | Rv1734c | No group | Conserved hypothetical protein | 395 |
M. tuberculosis | Rv0190 | OG5_136234 | Conserved protein | 394 |
M. tuberculosis | Rv3616c | OG5_237581 | ESX-1 secretion-associated protein A, EspA | 386 |
M. tuberculosis | Rv2694c | No group | Conserved protein | 383 |
M. tuberculosis | Rv0872c | OG5_129879 | PE-PGRS family protein PE_PGRS15 | 380 |
M. tuberculosis | Rv0251c | OG5_126935 | Heat shock protein Hsp (heat-stress-induced ribosome-binding protein A) | 378 |
M. tuberculosis | Rv3287c | No group | Anti-sigma factor RsbW (sigma negative effector) | 376 |
M. tuberculosis | Rv2031c | OG5_126935 | Heat shock protein HspX (alpha-crystallin homolog) (14 kDa antigen) (HSP16.3) | 374 |
M. tuberculosis | Rv0116c | OG5_237840 | Probable L,D-transpeptidase LdtA | 367 |
M. tuberculosis | Rv0197 | OG5_175709 | Possible oxidoreductase | 362 |
M. tuberculosis | Rv1285 | OG5_137554 | Probable sulfate adenylyltransferase subunit 2 CysD | 357 |
M. tuberculosis | Rv3132c | OG5_153508 | Two component sensor histidine kinase DevS | 350 |
M. tuberculosis | Rv0137c | OG5_126847 | Probable peptide methionine sulfoxide reductase MsrA (protein-methionine-S-oxide ... | 347 |
M. tuberculosis | Rv0810c | OG5_237775 | Conserved hypothetical protein | 346 |
M. tuberculosis | Rv2295 | OG5_230482 | Conserved hypothetical protein | 345 |
M. tuberculosis | Rv0467 | OG5_129572 | Isocitrate lyase Icl (isocitrase) (isocitratase) | 341 |
M. tuberculosis | Rv2029c | OG5_132575 | 6-phosphofructokinase PfkB (phosphohexokinase) (phosphofructokinase) | 336 |
M. tuberculosis | Rv2710 | OG5_237645 | RNA polymerase sigma factor SigB | 336 |
M. tuberculosis | Rv3380c | OG5_128670 | Probable transposase | 332 |
M. tuberculosis | Rv1221 | OG5_132054 | Alternative RNA polymerase sigma factor SigE | 331 |
M. tuberculosis | Rv3484 | OG5_213861 | Possible conserved protein CpsA | 330 |
M. tuberculosis | Rv2358 | OG5_155588 | Probable transcriptional regulatory protein SmtB (probably ArsR-family) | 330 |
M. tuberculosis | Rv3371 | OG5_133846 | Possible triacylglycerol synthase (diacylglycerol acyltransferase) | 329 |