Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.
2253 records found | Showing page 1 of 91 (records 1-25) | Number of records to display | Find orthologs in
| Organism | Name | Ortholog group | Product | Weight |
|---|---|---|---|---|
| M. tuberculosis | Rv0969 | OG5_126855 | Probable metal cation transporter P-type ATPase CtpV | 10 |
| M. tuberculosis | Rv0859 | OG5_159023 | Possible acyl-CoA thiolase FadA | 10 |
| M. tuberculosis | Rv1521 | OG5_127582 | Probable fatty-acid-AMP ligase FadD25 (fatty-acid-AMP synthetase) (fatty-acid-AM ... | 10 |
| M. tuberculosis | Rv1345 | OG5_158780 | Probable fatty acyl-AMP ligase MbtM | 10 |
| M. tuberculosis | Rv0112 | OG5_149659 | Possible GDP-mannose 4,6-dehydratase Gca (GDP-D-mannose dehydratase) | 10 |
| M. tuberculosis | Rv0237 | OG5_130549 | Probable conserved lipoprotein LpqI | 10 |
| M. tuberculosis | Rv3886c | OG5_159793 | Probable alanine and proline rich membrane-anchored mycosin MycP2 (serine protea ... | 10 |
| M. tuberculosis | Rv0191 | OG5_134076 | Probable conserved integral membrane protein | 10 |
| M. tuberculosis | Rv0523c | OG5_239116 | Conserved protein | 10 |
| M. tuberculosis | Rv0597c | OG5_157133 | Conserved hypothetical protein | 10 |
| M. tuberculosis | Rv0858c | OG5_126697 | Probable N-succinyldiaminopimelate aminotransferase DapC (DAP-at) | 10 |
| M. tuberculosis | Rv0958 | OG5_168869 | Possible magnesium chelatase | 10 |
| M. tuberculosis | Rv1319c | OG5_176490 | Possible adenylate cyclase (ATP pyrophosphate-lyase) (adenylyl cyclase) | 10 |
| M. tuberculosis | Rv1353c | OG5_178549 | Probable transcriptional regulatory protein | 10 |
| M. tuberculosis | Rv1357c | OG5_171565 | Conserved hypothetical protein | 10 |
| M. tuberculosis | Rv3357 | OG5_150453 | Antitoxin RelJ | 10 |
| M. tuberculosis | Rv3871 | OG5_237539 | ESX conserved component EccCb1. ESX-1 type VII secretion system protein. | 10 |
| M. tuberculosis | Rv3895c | No group | ESX conserved component EccB2. ESX-2 type VII secretion system protein. Probable ... | 10 |
| M. tuberculosis | Rv0033 | No group | Probable acyl carrier protein AcpA (ACP) | 9 |
| M. tuberculosis | Rv0238 | OG5_191242 | Possible transcriptional regulatory protein (probably TetR-family) | 9 |
| M. tuberculosis | Rv0189c | OG5_128618 | Probable dihydroxy-acid dehydratase IlvD (dad) | 8 |
| M. tuberculosis | Rv3873 | OG5_237538 | PPE family protein PPE68 | 8 |
| M. tuberculosis | Rv0995 | OG5_140277 | Ribosomal-protein-alanine acetyltransferase RimJ (acetylating enzyme for N-termi ... | 8 |
| M. tuberculosis | Rv0702 | OG5_127316 | 50S ribosomal protein L4 RplD | 8 |
| M. tuberculosis | Rv1500 | OG5_127079 | Probable glycosyltransferase | 8 |