Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.
2253 records found | Showing page 2 of 91 (records 26-50) | Number of records to display | Find orthologs in
| Organism | Name | Ortholog group | Product | Weight |
|---|---|---|---|---|
| M. tuberculosis | Rv3060c | OG5_153446 | Probable transcriptional regulatory protein (probably GntR-family) | 8 |
| M. tuberculosis | Rv3070 | OG5_131042 | Probable conserved integral membrane protein | 8 |
| M. tuberculosis | Rv1464 | OG5_128800 | Probable cysteine desulfurase Csd | 7 |
| M. tuberculosis | Rv0287 | OG5_204582 | ESAT-6 like protein EsxG (conserved protein TB9.8) | 7 |
| M. tuberculosis | Rv0400c | OG5_129299 | Acyl-CoA dehydrogenase FadE7 | 7 |
| M. tuberculosis | Rv1479 | OG5_130615 | Probable transcriptional regulatory protein MoxR1 | 7 |
| M. tuberculosis | Rv2057c | OG5_129957 | 50S ribosomal protein L33 RpmG1 | 7 |
| M. tuberculosis | Rv0361 | OG5_237574 | Probable conserved membrane protein | 7 |
| M. tuberculosis | Rv3806c | OG5_155572 | Decaprenylphosphoryl-5-phosphoribose (DPPR) synthase (decaprenyl-phosphate 5-pho ... | 7 |
| M. tuberculosis | Rv1658 | OG5_127707 | Probable argininosuccinate synthase ArgG | 5 |
| M. tuberculosis | Rv0917 | OG5_133159 | Possible glycine betaine transport integral membrane protein BetP | 5 |
| M. tuberculosis | Rv1568 | OG5_128068 | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase BioA | 5 |
| M. tuberculosis | Rv1092c | OG5_141174 | Probable pantothenate kinase CoaA (pantothenic acid kinase) | 5 |
| M. tuberculosis | Rv3484 | OG5_213861 | Possible conserved protein CpsA | 5 |
| M. tuberculosis | Rv1286 | OG5_168022 | Probable bifunctional enzyme CysN/CysC: sulfate adenyltransferase (subunit 1) + ... | 5 |
| M. tuberculosis | Rv0824c | OG5_137533 | Probable acyl-[acyl-carrier protein] desaturase DesA1 (acyl-[ACP] desaturase) (s ... | 5 |
| M. tuberculosis | Rv0350 | OG5_126744 | Probable chaperone protein DnaK (heat shock protein 70) (heat shock 70 kDa prote ... | 5 |
| M. tuberculosis | Rv3663c | OG5_134183 | Probable dipeptide-transport ATP-binding protein ABC transporter DppD | 5 |
| M. tuberculosis | Rv2938 | OG5_131341 | Probable daunorubicin-dim-transport integral membrane protein ABC transporter Dr ... | 5 |
| M. tuberculosis | Rv2214c | OG5_176297 | Possible short-chain dehydrogenase EphD | 5 |
| M. tuberculosis | Rv0134 | OG5_142324 | Possible epoxide hydrolase EphF (epoxide hydratase) (arene-oxide hydratase) | 5 |
| M. tuberculosis | Rv0288 | OG5_204581 | Low molecular weight protein antigen 7 EsxH (10 kDa antigen) (CFP-7) (protein TB ... | 5 |
| M. tuberculosis | Rv1038c | OG5_166835 | ESAT-6 like protein EsxJ (ESAT-6 like protein 2) | 5 |
| M. tuberculosis | Rv1197 | OG5_166835 | ESAT-6 like protein EsxK (ESAT-6 like protein 3) | 5 |
| M. tuberculosis | Rv3444c | OG5_237578 | Putative ESAT-6 like protein EsxT | 5 |