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Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.
2253 records found | Showing page 90 of 91 (records 2226-2250) | Number of records to display | Find orthologs in
| Organism | Name | Ortholog group | Product | Weight |
|---|---|---|---|---|
| M. tuberculosis | Rv3789 | OG5_216766 | GTRA family protein | -11 |
| M. tuberculosis | Rv3107c | OG5_130256 | Possible alkyldihydroxyacetonephosphate synthase AgpS (alkyl-DHAP synthase) (alk ... | -12 |
| M. tuberculosis | Rv3136 | OG5_135481 | PPE family protein PPE51 | -12 |
| M. tuberculosis | Rv0259c | OG5_133515 | Conserved hypothetical protein | -12 |
| M. tuberculosis | Rv0311 | No group | Unknown protein | -12 |
| M. tuberculosis | Rv0458 | OG5_126638 | Probable aldehyde dehydrogenase | -12 |
| M. tuberculosis | Rv0516c | OG5_184388 | Possible anti-anti-sigma factor | -12 |
| M. tuberculosis | Rv1892 | No group | Probable membrane protein | -12 |
| M. tuberculosis | Rv2169c | OG5_237633 | Probable conserved transmembrane protein | -12 |
| M. tuberculosis | Rv2488c | OG5_160474 | Probable transcriptional regulatory protein (LuxR-family) | -12 |
| M. tuberculosis | Rv2527 | OG5_173651 | Possible toxin VapC17 | -12 |
| M. tuberculosis | Rv2683 | OG5_237449 | Conserved protein | -12 |
| M. tuberculosis | Rv2730 | No group | Hypothetical protein | -12 |
| M. tuberculosis | Rv2983 | OG5_237715 | Conserved hypothetical alanine rich protein | -12 |
| M. tuberculosis | Rv3448 | No group | ESX conserved component EccD4. ESX-4 type VII secretion system protein. Probable ... | -12 |
| M. tuberculosis | Rv0621 | No group | Possible membrane protein | -13 |
| M. tuberculosis | Rv1354c | OG5_128712 | Conserved hypothetical protein | -13 |
| M. tuberculosis | Rv2286c | No group | Conserved hypothetical protein | -13 |
| M. tuberculosis | Rv2410c | OG5_145053 | Conserved protein | -13 |
| M. tuberculosis | Rv3856c | OG5_130965 | Conserved hypothetical protein | -13 |
| M. tuberculosis | Rv1964 | OG5_130961 | Conserved hypothetical integral membrane protein YrbE3A | -13 |
| M. tuberculosis | Rv2744c | OG5_182550 | Conserved 35 kDa alanine rich protein | -13 |
| M. tuberculosis | Rv3257c | OG5_128112 | Probable phosphomannomutase PmmA (PMM) (phosphomannose mutase) | -14 |
| M. tuberculosis | Rv1760 | OG5_133846 | Possible triacylglycerol synthase (diacylglycerol acyltransferase) | -14 |
| M. tuberculosis | Rv3670 | OG5_130074 | Possible epoxide hydrolase EphE (epoxide hydratase) (arene-oxide hydratase) | -15 |