Target list

Search results for query: Weighted list for comparison of PLOS-NTD's vs. this B. malayi targets prioritization

You can Modify weights (moves query to your history allowing re-weight functionality) to match your needs

  • Score for genes in query #41 (Bma all proteins): 1
  • Score for genes in query #27 (B. malayi orthologs of C. elegans genes differentially expressed in neurons): 30
  • Score for genes in query #28 (Bma druggable precedence by similarity to starlite targets): 30
  • Score for genes in query #39 (Bma in PDB): 5
  • Score for genes in query #31 (Bma pubmed): 2
  • Score for genes in query #23 (B. malayi orthologs of C. elegans genes differentially expressed in muscle): 30
  • Score for genes in query #36 (Bma - morphology defect in Cel): 20
  • Score for genes in query #40 (Bma assayable): 5
  • Score for genes in query #34 (Bma - growth defect in Cel): 20
  • Score for genes in query #29 (Bma - sterile in Cel): 20
  • Score for genes in query #32 (Bma in Cel): 10
  • Score for genes in query #45 ( top-100 of ranked list for PLOS-NTD; Posted List 361, No tissue-differential gene expression data): 0
  • Score for genes in query #38 (Bma any EC): 10
  • Score for genes in query #30 (Bma modbase): 2
  • Score for genes in query #33 (Bma - embryonic lethal/arrest in Cel): 30
  • Score for genes in query #44 ( top-25 of ranked list for PLOS-NTD; Posted List 361, No tissue-differential gene expression data): 0
  • Score for genes in query #35 (Bma - larval/adult lethal/arrest in Cel): 40
  • Score for genes in query #37 (Bma any essentiality): 5

Convert this list of targets into a list of drugs:

Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.

Retrieve:

11305 records found | Showing page 2 of 453 (records 26-50) | Number of records to display | Find orthologs in

  Organism   Name     Ortholog group   Product Weight
B. malayi   Bm1_16695   OG5_191556   Phosphopantetheine attachment site family protein 188
B. malayi   Bm1_39720   OG5_128374   Hypothetical 52.8 kDa protein T05E11.5 in chromosome IV 188
B. malayi   Bm1_34925   OG5_126595   actin 1 188
B. malayi   Bm1_28565   OG5_127730   T-complex protein 1, beta subunit 188
B. malayi   Bm1_41290   OG5_127141   Ser/Thr protein phosphatase family protein 188
B. malayi   Bm1_34930   OG5_126595   actin 2 188
B. malayi   Bm1_21725   OG5_126595   actin 2 188
B. malayi   Bm1_31340   OG5_126705   vacuolar proton pump 188
B. malayi   Bm1_34045   OG5_127141   type 2A protein phosphatase catalytic subunit 188
B. malayi   Bm1_10270   OG5_127730   T-complex protein 1, beta subunit 186
B. malayi   Bm1_21705   OG5_126595   actin 1 186
B. malayi   Bm1_31540   OG5_126779   2-oxoglutarate dehydrogenase E1 component, mitochondrial precursor 183
B. malayi   Bm1_01775   OG5_126696   ADP-ribosylation factor 1 178
B. malayi   Bm1_35670   OG5_126577   Myosin tail family protein 178
B. malayi   Bm1_30925   OG5_192404   MyTH4 domain containing protein 178
B. malayi   Bm1_32050   OG5_127090   60S ribosomal protein L5 178
B. malayi   Bm1_40715   OG5_126577   myosin heavy chain 178
B. malayi   Bm1_57025   OG5_126696   ADP-ribosylation factor 1 178
B. malayi   Bm1_50805   OG5_126577   Myosin tail family protein 178
B. malayi   Bm1_30920   OG5_127340   Myosin head containing protein 178
B. malayi   Bm1_19405   OG5_129757   Homeobox protein ceh-20 178
B. malayi   Bm1_28835   OG5_128511   Transcription initiation factor IIA, gamma subunit, helical domain containing pr ... 178
B. malayi   Bm1_56775   OG5_127205   40S ribosomal protein S29 178
B. malayi   Bm1_32860   OG5_126723   Valyl-tRNA synthetase 178
B. malayi   Bm1_14060   OG5_126577   myosin heavy chain B (MHC B) 178

Showing page 2 (records 26-50) of 453