Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.
550 records found | Showing page 1 of 22 (records 1-25) | Number of records to display | Find orthologs in
| Organism | Name | Ortholog group | Product |
|---|---|---|---|
| P. falciparum | PF3D7_0102900 | OG5_127227 | aspartate--tRNA ligase |
| P. falciparum | PF3D7_0104400 | OG5_130373 | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase |
| P. falciparum | PF3D7_0106100 | OG5_127946 | V-type proton ATPase subunit C, putative |
| P. falciparum | PF3D7_0106800 | OG5_126724 | ras-related protein Rab-5C |
| P. falciparum | PF3D7_0109500 | OG5_128089 | N-acetyltransferase, putative |
| P. falciparum | PF3D7_0109800 | OG5_127036 | phenylalanine--tRNA ligase alpha subunit |
| P. falciparum | PF3D7_0110400 | OG5_128243 | DNA-directed RNA polymerase II subunit RPB9, putative |
| P. falciparum | PF3D7_0110600 | OG5_126948 | phosphatidylinositol-4-phosphate 5-kinase |
| P. falciparum | PF3D7_0111500 | OG5_126886 | UMP-CMP kinase, putative |
| P. falciparum | PF3D7_0112200 | OG5_144709 | multidrug resistance-associated protein 1 |
| P. falciparum | PF3D7_0202700 | OG5_126937 | octaprenyl pyrophosphate synthase |
| P. falciparum | PF3D7_0203900 | OG5_132022 | 5'-3' exonuclease, N-terminal resolvase-like domain, putative |
| P. falciparum | PF3D7_0204500 | OG5_126737 | aspartate transaminase |
| P. falciparum | PF3D7_0204800 | OG5_162652 | 3'-5' exonuclease, putative |
| P. falciparum | PF3D7_0204900 | OG5_127211 | ubiE/COQ5 methyltransferase, putative |
| P. falciparum | PF3D7_0205500 | OG5_128606 | DNA-directed RNA polymerase II 16 kDa subunit, putative |
| P. falciparum | PF3D7_0206000 | OG5_128675 | DNA repair protein RAD2, putative |
| P. falciparum | PF3D7_0206700 | OG5_130883 | adenylosuccinate lyase |
| P. falciparum | PF3D7_0208400 | OG5_162066 | conserved Plasmodium protein, unknown function |
| P. falciparum | PF3D7_0209100 | OG5_137339 | phospholipase A2, putative |
| P. falciparum | PF3D7_0209300 | OG5_130616 | 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase |
| P. falciparum | PF3D7_0211400 | OG5_129509 | beta-ketoacyl-ACP synthase III |
| P. falciparum | PF3D7_0211700 | OG5_130251 | tyrosine kinase-like protein, putative |
| P. falciparum | PF3D7_0211800 | OG5_126756 | asparagine--tRNA ligase |
| P. falciparum | PF3D7_0215000 | OG5_129177 | acyl-CoA synthetase |