Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.
3515 records found | Showing page 1 of 141 (records 1-25) | Number of records to display | Find orthologs in
Organism | Name | Ortholog group | Product | Weight |
---|---|---|---|---|
P. falciparum | PF3D7_1022800 | OG5_130276 | 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase | 130 |
P. falciparum | PF3D7_1323000 | OG5_130367 | beta-hydroxyacyl-ACP dehydratase | 130 |
P. falciparum | PF3D7_1327600 | OG5_131883 | nicotinamide/nicotinic acid mononucleotide adenylyltransferase | 130 |
P. falciparum | PF3D7_1467300 | OG5_130462 | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | 130 |
P. falciparum | PF3D7_0104400 | OG5_130373 | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase | 130 |
P. falciparum | PF3D7_0209300 | OG5_130616 | 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | 130 |
P. falciparum | PF3D7_0211400 | OG5_129509 | beta-ketoacyl-ACP synthase III | 130 |
P. falciparum | PF3D7_0219500 | OG5_128305 | pseudouridine synthase, putative | 130 |
P. falciparum | PF3D7_0420200 | OG5_130884 | holo-[acyl-carrier-protein] synthase, putative | 130 |
P. falciparum | PF3D7_0503100 | OG5_130885 | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, putative | 130 |
P. falciparum | PF3D7_0615100 | OG5_130466 | enoyl-acyl carrier reductase | 130 |
P. falciparum | PF3D7_1223300 | OG5_129568 | DNA gyrase subunit A | 130 |
P. falciparum | PF3D7_1350700 | OG5_130478 | N6-adenine-specific methylase, putative | 110 |
P. falciparum | PF3D7_1365100 | OG5_149624 | mitochondrial ribosomal protein S17 precursor, putative | 110 |
P. falciparum | PF3D7_1033400 | OG5_127435 | haloacid dehalogenase-like hydrolase | 110 |
P. falciparum | PF3D7_1469000 | OG5_130791 | translation initiation factor IF-1 | 110 |
P. falciparum | PF3D7_0206100 | OG5_127283 | cysteine desulfuration protein SufE | 110 |
P. falciparum | PF3D7_0503000 | OG5_130709 | 50S ribosomal protein L28, apicoplast, putative | 110 |
P. falciparum | PF3D7_0613400 | OG5_130467 | apicoplast ribosomal protein L18 precursor, putative | 110 |
P. falciparum | PF3D7_1226300 | OG5_138778 | haloacid dehalogenase-like hydrolase, putative | 110 |
P. falciparum | PF3D7_0716600 | OG5_128800 | cysteine desulfurase | 100 |
P. falciparum | PF3D7_0810800 | OG5_128803 | hydroxymethyldihydropterin pyrophosphokinase-dihydropteroate synthase | 100 |
P. falciparum | PF3D7_1435300 | OG5_126892 | NAD(P)H-dependent glutamate synthase, putative | 100 |
P. falciparum | PF3D7_0520500 | OG5_128612 | phosphomethylpyrimidine kinase, putative | 100 |
P. falciparum | PF3D7_0623000 | OG5_128304 | chorismate synthase | 100 |