Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.
57 records found | Showing page 1 of 3 (records 1-25) | Number of records to display | Find orthologs in
Organism | Name | Ortholog group | Product |
---|---|---|---|
T. brucei | Tb11.v5.0356 | OG5_126851 | cytidine triphosphate synthase, putative |
T. brucei | Tb11.v5.0531 | OG5_127143 | fructose-bisphosphate aldolase, glycosomal, putative |
T. brucei | Tb427.10.6950 | No group | sterol 24-c-methyltransferase, putative |
T. brucei | Tb927.1.2530 | OG5_126569 | histone H3, putative |
T. brucei | Tb927.1.2580 | OG5_146937 | exosome-associated protein 1 |
T. brucei | Tb927.1.700 | OG5_126776 | phosphoglycerate kinase |
T. brucei | Tb927.10.10390 | OG5_126785 | trypanothione reductase |
T. brucei | Tb927.10.12370 | OG5_128698 | gamma-glutamylcysteine synthetase |
T. brucei | Tb927.10.13860 | OG5_128053 | GPI-anchor transamidase subunit 8 (GPI8) |
T. brucei | Tb927.10.14240 | OG5_127597 | N-myristoyltransferase |
T. brucei | Tb927.10.1630 | OG5_127149 | atp-binding cassette sub-family e member 1 |
T. brucei | Tb927.10.1900 | OG5_126736 | DNA topoisomerase IA, putative |
T. brucei | Tb927.10.2890 | OG5_126698 | enolase |
T. brucei | Tb927.10.5560 | OG5_128622 | GPI alpha-mannosyltransferase III |
T. brucei | Tb927.10.7090 | OG5_130283 | Alternative oxidase, mitochondrial |
T. brucei | Tb927.11.11030 | OG5_128529 | exosome-associated protein 4 |
T. brucei | Tb927.11.12080 | OG5_128077 | N-acetyl-D-glucosaminylphosphatidylinositol de-N-acetylase |
T. brucei | Tb927.11.13730 | OG5_126750 | ornithine decarboxylase |
T. brucei | Tb927.11.15750 | OG5_126856 | AMP deaminase, putative |
T. brucei | Tb927.11.16410 | OG5_154710 | enolase, putative |
T. brucei | Tb927.11.16600 | OG5_154964 | exosome-associated protein 2 |
T. brucei | Tb927.11.2730 | OG5_126853 | UDP-galactose 4-epimerase |
T. brucei | Tb927.11.3850 | OG5_126856 | AMP deaminase, putative |
T. brucei | Tb927.11.3880 | OG5_143355 | actin, putative |
T. brucei | Tb927.11.6230 | OG5_127102 | protein transport protein SEC61 subunit alpha, putative |