Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.
390 records found | Showing page 1 of 16 (records 1-25) | Number of records to display | Find orthologs in
Organism | Name | Ortholog group | Product |
---|---|---|---|
T. brucei | Tb05.5K5.80 | OG5_145848 | calcium/calmodulin-dependent protein kinase, putative |
T. brucei | Tb10.v4.0088 | OG5_133835 | variant surface glycoprotein (VSG), putative |
T. brucei | Tb11.01.2730 | OG5_150840 | hypothetical protein, conserved |
T. brucei | Tb11.02.5420b | OG5_127162 | NADPH-cytochrome p450 reductase, putative |
T. brucei | Tb11.0330 | OG5_173080 | Cornifin (SPRR) family, putative |
T. brucei | Tb11.v5.0185 | OG5_146845 | hypothetical protein, conserved |
T. brucei | Tb11.v5.0307 | OG5_129633 | THT1 - hexose transporter, putative |
T. brucei | Tb11.v5.0387 | OG5_154593 | cell-division control protein 2 homolog 6, putative |
T. brucei | Tb11.v5.0474 | OG5_154473 | protein kinase, putative |
T. brucei | Tb11.v5.0671 | OG5_126748 | protein kinase A catalytic subunit, putative |
T. brucei | Tb11.v5.0718 | OG5_126888 | protein kinase, putative |
T. brucei | Tb11.v5.0831 | OG5_138981 | kinesin motor domain containing protein, putative |
T. brucei | Tb427.10.11860 | No group | hypothetical protein, conserved |
T. brucei | Tb427.10.15400 | No group | kinesin, putative |
T. brucei | Tb427.10.3900 | No group | protein kinase, putative |
T. brucei | Tb427.10.5940 | No group | (OTHER) NEK family, HsNEK1-like |
T. brucei | Tb427.10.6950 | No group | sterol 24-c-methyltransferase, putative |
T. brucei | Tb427tmp.160.0810 | OG5_129469 | kynureninase, putative |
T. brucei | Tb927.1.1000 | OG5_127409 | developmentally regulated phosphoprotein |
T. brucei | Tb927.1.1150 | OG5_145938 | zeta tubulin |
T. brucei | Tb927.1.1350 | OG5_127646 | kinesin heavy chain, putative |
T. brucei | Tb927.1.1530 | OG5_145823 | STE group serine/threonine-protein kinase, putative |
T. brucei | Tb927.1.2100 | OG5_135138 | Calpain-like protein 1.1 |
T. brucei | Tb927.1.2110 | OG5_146880 | Calpain-like protein 1.2 |
T. brucei | Tb927.1.2120 | OG5_156130 | Calpain-like protein CALP1.3 |