Target list

Search results for query: T. brucei targets - composite weighted query (DSR)

  • Score for genes in query #29 (Druggability precedent (>0.6)): 35
  • Score for genes in query #5 (Present in all TriTryps): 25
  • Score for genes in query #4 (T. brucei models): 30
  • Score for genes in query #6 (T. brucei, NOT human): 25
  • Score for genes in query #36 (T. brucei 3D structures): 50
  • Score for genes in query #33 (T. brucei no TM domains): 20
  • Score for genes in query #34 (T. brucei published): 35
  • Score for genes in query #27 (T. brucei <100kDa): 20
  • Score for genes in query #35 (T. brucei lethal (KO or KD)): 50
  • Score for genes in query #2 (T. brucei enzymes): 100
  • Score for genes in query #30 (Compound desirability (>0.3)): 35
  • Score for genes in query #7 (Essential (in any organism)): 40

Convert this list of targets into a list of drugs:

Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.

Retrieve:

8361 records found | Showing page 335 of 335 (records 8351-8361) | Number of records to display | Find orthologs in

  Organism   Name     Ortholog group   Product Weight
T. brucei   Tb927.4.2050   OG5_247500   hypothetical protein 20
T. brucei   Tb927.9.780     No group hypothetical protein 20
T. brucei   Tb427.06.420     No group hypothetical protein 20
T. brucei   Tb927.10.12570   OG5_206566   hypothetical protein 20
T. brucei   Tb927.5.4000   OG5_247524   hypothetical protein 20
T. brucei   Tb927.10.9610   OG5_206561   hypothetical protein 20
T. brucei   Tb927.9.6570     No group hypothetical protein, conserved 20
T. brucei   Tb927.6.260   OG5_247820   hypothetical protein 20
T. brucei   Tb927.8.2320     No group hypothetical protein 20
T. brucei   Tb927.10.11710     No group hypothetical protein 20
T. brucei   Tb927.5.2760   OG5_174200   UDP-Gal or UDP-GlcNAc-dependent glycosyltransferase, putative 20

Showing page 335 (records 8351-8361) of 335