Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.
2250 records found | Showing page 2 of 90 (records 26-50) | Number of records to display | Find orthologs in
Organism | Name | Ortholog group | Product | Weight |
---|---|---|---|---|
M. tuberculosis | Rv0005 | OG5_128755 | DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisome ... | 160 |
M. tuberculosis | Rv1266c | OG5_142551 | Probable transmembrane serine/threonine-protein kinase H PknH (protein kinase H) ... | 160 |
M. tuberculosis | Rv0682 | OG5_127680 | 30S ribosomal protein S12 RpsL | 160 |
M. tuberculosis | Rv3708c | OG5_128664 | Aspartate-semialdehyde dehydrogenase Asd (ASA dehydrogenase) (ASADH) (aspartic s ... | 155 |
M. tuberculosis | Rv1306 | OG5_134191 | Probable ATP synthase B chain AtpF | 155 |
M. tuberculosis | Rv0993 | OG5_131936 | UTP--glucose-1-phosphate uridylyltransferase GalU (UDP-glucose pyrophosphorylase ... | 155 |
M. tuberculosis | Rv0006 | OG5_129568 | DNA gyrase (subunit A) GyrA (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisome ... | 155 |
M. tuberculosis | Rv0524 | OG5_129427 | Probable glutamate-1-semialdehyde 2,1-aminomutase HemL (GSA) (glutamate-1-semial ... | 155 |
M. tuberculosis | Rv3398c | OG5_130660 | Probable multifunctional geranylgeranyl pyrophosphate synthetase IdsA1 (GGPP syn ... | 155 |
M. tuberculosis | Rv2210c | OG5_126731 | Branched-chain amino acid transaminase IlvE | 155 |
M. tuberculosis | Rv2995c | OG5_126870 | Probable 3-isopropylmalate dehydrogenase LeuB (beta-IPM dehydrogenase) (IMDH) (3 ... | 155 |
M. tuberculosis | Rv3441c | OG5_128112 | Probable phospho-sugar mutase / MrsA protein homolog | 155 |
M. tuberculosis | Rv2157c | OG5_132578 | Probable UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-al ... | 155 |
M. tuberculosis | Rv2156c | OG5_131597 | Probable phospho-N-acetylmuramoyl-pentappeptidetransferase MurX | 155 |
M. tuberculosis | Rv2421c | OG5_131883 | Probable nicotinate-nucleotide adenylyltransferase NadD (deamido-NAD(+) pyrophos ... | 155 |
M. tuberculosis | Rv3257c | OG5_128112 | Probable phosphomannomutase PmmA (PMM) (phosphomannose mutase) | 155 |
M. tuberculosis | Rv2883c | OG5_130032 | Probable uridylate kinase PyrH (UK) (uridine monophosphate kinase) (UMP kinase) | 155 |
M. tuberculosis | Rv1415 | OG5_127275 | Probable riboflavin biosynthesis protein RibA2 : GTP cyclohydrolase II + 3,4-dih ... | 155 |
M. tuberculosis | Rv3457c | OG5_130460 | Probable DNA-directed RNA polymerase (alpha chain) RpoA (transcriptase alpha cha ... | 155 |
M. tuberculosis | Rv0415 | OG5_144261 | Possible thiamine biosynthesis oxidoreductase ThiO | 155 |
M. tuberculosis | Rv0467 | OG5_129572 | Isocitrate lyase Icl (isocitrase) (isocitratase) | 150 |
M. tuberculosis | Rv1484 | OG5_130466 | NADH-dependent enoyl-[acyl-carrier-protein] reductase InhA (NADH-dependent enoyl ... | 150 |
M. tuberculosis | Rv2965c | OG5_132912 | Probable phosphopantetheine adenylyltransferase KdtB (pantetheine- phosphate ade ... | 150 |
M. tuberculosis | Rv2841c | OG5_131885 | Probable N utilization substance protein A NusA | 150 |
M. tuberculosis | Rv2533c | OG5_132731 | N utilization substance protein NusB (NusB protein) | 150 |