Target list

Search results for query: Wes VV TB Prioritized Targets: Structure, Enzyme, <600AA, essential, curated, not in human

  • Score for genes in query #59 (TB with Modeled structures): 20
  • Score for genes in query #54 (TB < 600 AA): 25
  • Score for genes in query #48 (TB curated): 50
  • Score for genes in query #58 (TB w/ solved structures): 30
  • Score for genes in query #63 (TB not in human): 10
  • Score for genes in query #60 (TB known essentials): 35
  • Score for genes in query #61 (TB E coli essentials): 20
  • Score for genes in query #52 (TB enzymes (any EC #)): 35
  • Score for genes in query #62 (TB essential in any species): 10

Convert this list of targets into a list of drugs:

Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.

Retrieve:

2250 records found | Showing page 90 of 90 (records 2226-2250) | Number of records to display | Find orthologs in

  Organism   Name     Ortholog group   Product Weight
M. tuberculosis   Rv2874   OG5_208929   Possible integral membrane C-type cytochrome biogenesis protein DipZ 20
M. tuberculosis   Rv0860   OG5_127588   Probable fatty oxidation protein FadB 20
M. tuberculosis   Rv0342     No group Isoniazid inductible gene protein IniA 20
M. tuberculosis   Rv1166   OG5_237698   Probable conserved lipoprotein LpqW 20
M. tuberculosis   Rv2381c     No group Polyketide synthetase MbtD (polyketide synthase) 20
M. tuberculosis   Rv2380c   OG5_126718   Peptide synthetase MbtE (peptide synthase) 20
M. tuberculosis   Rv2379c   OG5_126718   Peptide synthetase MbtF (peptide synthase) 20
M. tuberculosis   Rv0862c   OG5_237770   Conserved protein 20
M. tuberculosis   Rv1565c   OG5_222118   Conserved hypothetical membrane protein 20
M. tuberculosis   Rv1866   OG5_168843   Conserved protein 20
M. tuberculosis   Rv2345   OG5_163855   Possible conserved transmembrane protein 20
M. tuberculosis   Rv2864c   OG5_237708   Possible penicillin-binding lipoprotein 20
M. tuberculosis   Rv3239c   OG5_126664   Probable conserved transmembrane transport protein 20
M. tuberculosis   Rv3792   OG5_237552   Arabinofuranosyltransferase AftA 20
M. tuberculosis   Rv3805c   OG5_237549   Possible arabinofuranosyltransferase AftB 20
M. tuberculosis   Rv3876   OG5_152910   ESX-1 secretion-associated protein EspI. Conserved proline and alanine rich prot ... 20
M. tuberculosis   Rv3903c     No group Hypothetical alanine and proline rich protein 20
M. tuberculosis   Rv0120c   OG5_229506   Probable elongation factor G FusA2 (EF-G) 10
M. tuberculosis   Rv1020   OG5_131372   Probable transcription-repair coupling factor Mfd (TRCF) 10
M. tuberculosis   Rv0064   OG5_152620   Probable conserved transmembrane protein 10
M. tuberculosis   Rv0959   OG5_175719   Conserved hypothetical protein 10
M. tuberculosis   Rv1877   OG5_126664   Probable conserved integral membrane protein 10
M. tuberculosis   Rv2395   OG5_129625   Probable conserved integral membrane protein 10
M. tuberculosis   Rv2567   OG5_164866   Conserved hypothetical alanine and leucine rich protein 10
M. tuberculosis   Rv1759c   OG5_129879   PE-PGRS family protein Wag22 10

Showing page 90 (records 2226-2250) of 90