Target list

Search results for query: Uploaded gene list of query #27 - druggable and absent in humans

  • Query: Uploaded list
Show: all curated predicted compounds associated with these genes.

Compounds have been manually associated with targets based on literature curation (curated), and transitively associated with direct orthologs (predicted). Please note that a link between a compound and a target does not imply an outstanding activity (e.g. inhibition). In many cases the association serves the only purpose of showing that e.g. "compound X" has been tested against "target Y", even if there was no detectable activity in the assay. Information about each assay and its outcome is available for each compound.

23 records found | Showing page 1 of 1 (records 1-23) | Number of records to display | Find orthologs in

  Organism   Name     Ortholog group   Product
M. tuberculosis   Rv2523c   OG5_130884   holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pant ...
M. tuberculosis   Rv2538c   OG5_127183   3-dehydroquinate synthase AroB
M. tuberculosis   Rv2537c   OG5_132746   3-dehydroquinate dehydratase AroD (AROQ) (3-dehydroquinase) (type II dhqase)
M. tuberculosis   Rv2068c   OG5_143180   Class a beta-lactamase BlaC
M. tuberculosis   Rv0766c   OG5_132455   Probable cytochrome P450 123 Cyp123
M. tuberculosis   Rv2266   OG5_132455   Probable cytochrome P450 124 Cyp124
M. tuberculosis   Rv2268c   OG5_132455   Probable cytochrome P450 128 Cyp128
M. tuberculosis   Rv1256c   OG5_132455   Probable cytochrome P450 130 Cyp130
M. tuberculosis   Rv3518c   OG5_132455   Probable cytochrome P450 monooxygenase 142 Cyp142
M. tuberculosis   Rv1547   OG5_132143   Probable DNA polymerase III (alpha chain) DnaE1 (DNA nucleotidyltransferase)
M. tuberculosis   Rv0533c   OG5_129509   3-oxoacyl-[acyl-carrier-protein] synthase III FabH (beta-ketoacyl-ACP synthase I ...
M. tuberculosis   Rv3804c   OG5_210859   Secreted antigen 85-a FbpA (mycolyl transferase 85A) (fibronectin-binding protei ...
M. tuberculosis   Rv1886c   OG5_237749   Secreted antigen 85-B FbpB (85B) (antigen 85 complex B) (mycolyl transferase 85B ...
M. tuberculosis   Rv0129c   OG5_237839   Secreted antigen 85-C FbpC (85C) (antigen 85 complex C) (AG58C) (mycolyl transfe ...
M. tuberculosis   Rv3803c   OG5_237550   Secreted MPT51/MPB51 antigen protein FbpD (MPT51/MPB51 antigen 85 complex C) (AG ...
M. tuberculosis   Rv1601   OG5_129258   Probable imidazole glycerol-phosphate dehydratase HisB
M. tuberculosis   Rv1484   OG5_130466   NADH-dependent enoyl-[acyl-carrier-protein] reductase InhA (NADH-dependent enoyl ...
M. tuberculosis   Rv0091   OG5_130719   Probable bifunctional MTA/SAH nucleosidase Mtn: 5'-methylthioadenosine nucleosid ...
M. tuberculosis   Rv2157c   OG5_132578   Probable UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-al ...
M. tuberculosis   Rv2156c   OG5_131597   Probable phospho-N-acetylmuramoyl-pentappeptidetransferase MurX
M. tuberculosis   Rv0769   OG5_169253   Probable dehydrogenase/reductase
M. tuberculosis   Rv1523   OG5_176228   Probable methyltransferase
M. tuberculosis   Rv2952   OG5_149693   Possible methyltransferase (methylase)

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TDR Targets Development Release v6, Revision: 1335 (10.Aug.2018)
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