Target list

Search results for query: T. brucei lethal (KO or KD)

  • species: tbr
  • phenotype: Q=PATO:0000718
Show: all curated predicted compounds associated with these genes.

Compounds have been manually associated with targets based on literature curation (curated), and transitively associated with direct orthologs (predicted). Please note that a link between a compound and a target does not imply an outstanding activity (e.g. inhibition). In many cases the association serves the only purpose of showing that e.g. "compound X" has been tested against "target Y", even if there was no detectable activity in the assay. Information about each assay and its outcome is available for each compound.

57 records found | Showing page 1 of 3 (records 1-25) | Number of records to display | Find orthologs in

  Organism   Name     Ortholog group   Product
T. brucei   Tb11.v5.0356   OG5_126851   cytidine triphosphate synthase, putative
T. brucei   Tb11.v5.0531   OG5_127143   fructose-bisphosphate aldolase, glycosomal, putative
T. brucei   Tb427.10.6950     No group sterol 24-c-methyltransferase, putative
T. brucei   Tb927.1.2530   OG5_126569   histone H3, putative
T. brucei   Tb927.1.2580   OG5_146937   exosome-associated protein 1
T. brucei   Tb927.1.700   OG5_126776   phosphoglycerate kinase
T. brucei   Tb927.10.10390   OG5_126785   trypanothione reductase
T. brucei   Tb927.10.12370   OG5_128698   gamma-glutamylcysteine synthetase
T. brucei   Tb927.10.13860   OG5_128053   GPI-anchor transamidase subunit 8 (GPI8)
T. brucei   Tb927.10.14240   OG5_127597   N-myristoyltransferase
T. brucei   Tb927.10.1630   OG5_127149   atp-binding cassette sub-family e member 1
T. brucei   Tb927.10.1900   OG5_126736   DNA topoisomerase IA, putative
T. brucei   Tb927.10.2890   OG5_126698   enolase
T. brucei   Tb927.10.5560   OG5_128622   GPI alpha-mannosyltransferase III
T. brucei   Tb927.10.7090   OG5_130283   Alternative oxidase, mitochondrial
T. brucei   Tb927.11.11030   OG5_128529   exosome-associated protein 4
T. brucei   Tb927.11.12080   OG5_128077   N-acetyl-D-glucosaminylphosphatidylinositol de-N-acetylase
T. brucei   Tb927.11.13730   OG5_126750   ornithine decarboxylase
T. brucei   Tb927.11.15750   OG5_126856   AMP deaminase, putative
T. brucei   Tb927.11.16410   OG5_154710   enolase, putative
T. brucei   Tb927.11.16600   OG5_154964   exosome-associated protein 2
T. brucei   Tb927.11.2730   OG5_126853   UDP-galactose 4-epimerase
T. brucei   Tb927.11.3850   OG5_126856   AMP deaminase, putative
T. brucei   Tb927.11.3880   OG5_143355   actin, putative
T. brucei   Tb927.11.6230   OG5_127102   protein transport protein SEC61 subunit alpha, putative

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TDR Targets Development Release v6, Revision: 1335 (10.Aug.2018)
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