Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.
164 records found | Showing page 1 of 7 (records 1-25) | Number of records to display | Find orthologs in
Organism | Name | Ortholog group | Product |
---|---|---|---|
L. major | LmjF.01.0480 | OG5_139136 | beta eliminating lyase,putative |
L. major | LmjF.04.0060 | OG5_145769 | DNA topoisomerase type IB small subunit |
L. major | LmjF.04.1160 | OG5_127400 | |
L. major | LmjF.05.0350 | OG5_126785 | trypanothione reductase |
L. major | LmjF.05.0970 | OG5_127129 | 3-mercaptopyruvate sulfurtransferase |
L. major | LmjF.06.0120 | OG5_127452 | cyclophilin 2 |
L. major | LmjF.06.0560 | OG5_143192 | deoxyuridine triphosphatase, putative,dUTP diphosphatase |
L. major | LmjF.06.1270 | OG5_128228 | coproporphyrinogen III oxidase |
L. major | LmjF.08.0290 | OG5_126676 | iron superoxide dismutase |
L. major | LmjF.08.1030 | OG5_126607 | cathepsin L-like protease |
L. major | LmjF.08.1060 | OG5_126607 | cathepsin L-like protease |
L. major | LmjF.08.1080 | OG5_126607 | cathepsin L-like protease |
L. major | LmjF.08.1200 | OG5_148308 | hypothetical protein, conserved |
L. major | LmjF.09.0770 | OG5_129201 | oligopeptidase b |
L. major | LmjF.10.0200 | OG5_148335 | mitogen-activated protein kinase, putative,map kinase-like protein |
L. major | LmjF.10.0460 | OG5_126749 | GP63, leishmanolysin |
L. major | LmjF.10.0465 | OG5_126749 | GP63, leishmanolysin |
L. major | LmjF.10.0470 | OG5_126749 | GP63, leishmanolysin |
L. major | LmjF.10.0480 | OG5_126749 | GP63, leishmanolysin |
L. major | LmjF.10.0510 | OG5_126704 | glycerol-3-phosphate dehydrogenase [NAD ], glycosomal |
L. major | LmjF.10.1230 | OG5_183282 | hypothetical protein, conserved |
L. major | LmjF.10.1240 | OG5_183283 | hypothetical protein, conserved |
L. major | LmjF.10.1250 | OG5_183284 | hypothetical protein, conserved |
L. major | LmjF.10.1260 | OG5_161838 | hypothetical protein, conserved |
L. major | LmjF.10.1270 | OG5_183285 | hypothetical protein, conserved |