Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.
394 records found | Showing page 1 of 16 (records 1-25) | Number of records to display | Find orthologs in
| Organism | Name | Ortholog group | Product |
|---|---|---|---|
| M. tuberculosis | Rv0002 | OG5_132148 | DNA polymerase III (beta chain) DnaN (DNA nucleotidyltransferase) |
| M. tuberculosis | Rv0005 | OG5_128755 | DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisome ... |
| M. tuberculosis | Rv0006 | OG5_129568 | DNA gyrase (subunit A) GyrA (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisome ... |
| M. tuberculosis | Rv0009 | OG5_128211 | Probable iron-regulated peptidyl-prolyl cis-trans isomerase A PpiA (PPIase A) (r ... |
| M. tuberculosis | Rv0013 | OG5_128663 | Possible anthranilate synthase component II TrpG (glutamine amidotransferase) |
| M. tuberculosis | Rv0014c | OG5_146588 | Transmembrane serine/threonine-protein kinase B PknB (protein kinase B) (STPK B) |
| M. tuberculosis | Rv0015c | OG5_155711 | Transmembrane serine/threonine-protein kinase A PknA (protein kinase A) (STPK A) |
| M. tuberculosis | Rv0032 | OG5_126783 | Possible 8-amino-7-oxononanoate synthase BioF2 (AONS) (8-amino-7-ketopelargonate ... |
| M. tuberculosis | Rv0035 | No group | Probable fatty-acid-CoA ligase FadD34 (fatty-acid-CoA synthetase) (fatty-acid-Co ... |
| M. tuberculosis | Rv0046c | OG5_139953 | myo-inositol-1-phosphate synthase Ino1 (inositol 1-phosphate synthetase) (D-gluc ... |
| M. tuberculosis | Rv0058 | OG5_131890 | Probable replicative DNA helicase DnaB |
| M. tuberculosis | Rv0070c | OG5_126679 | Serine hydroxymethyltransferase GlyA2 (serine methylase 2) (SHMT 2) |
| M. tuberculosis | Rv0075 | OG5_135774 | Probable aminotransferase |
| M. tuberculosis | Rv0092 | OG5_126855 | Cation transporter P-type ATPase a CtpA |
| M. tuberculosis | Rv0099 | OG5_163246 | Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-Co ... |
| M. tuberculosis | Rv0125 | OG5_171368 | Probable serine protease PepA (serine proteinase) (MTB32A) |
| M. tuberculosis | Rv0126 | OG5_126827 | Trehalose synthase TreS |
| M. tuberculosis | Rv0129c | OG5_237839 | Secreted antigen 85-C FbpC (85C) (antigen 85 complex C) (AG58C) (mycolyl transfe ... |
| M. tuberculosis | Rv0133 | OG5_141414 | GCN5-related N-acetyltransferase |
| M. tuberculosis | Rv0134 | OG5_142324 | Possible epoxide hydrolase EphF (epoxide hydratase) (arene-oxide hydratase) |
| M. tuberculosis | Rv0137c | OG5_126847 | Probable peptide methionine sulfoxide reductase MsrA (protein-methionine-S-oxide ... |
| M. tuberculosis | Rv0147 | OG5_127094 | Probable aldehyde dehydrogenase (NAD+) dependent |
| M. tuberculosis | Rv0153c | OG5_132308 | Phosphotyrosine protein phosphatase PTPB (protein-tyrosine-phosphatase) (PTPase) |
| M. tuberculosis | Rv0157 | OG5_127241 | Probable NAD(P) transhydrogenase (subunit beta) PntB [integral membrane protein] ... |
| M. tuberculosis | Rv0208c | OG5_127179 | Hypothetical methlytransferase (methylase) |