Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.
3198 records found | Showing page 1 of 128 (records 1-25) | Number of records to display | Find orthologs in
| Organism | Name | Ortholog group | Product |
|---|---|---|---|
| M. tuberculosis | Rv0001 | OG5_132291 | Chromosomal replication initiator protein DnaA |
| M. tuberculosis | Rv0002 | OG5_132148 | DNA polymerase III (beta chain) DnaN (DNA nucleotidyltransferase) |
| M. tuberculosis | Rv0003 | OG5_134856 | DNA replication and repair protein RecF (single-strand DNA binding protein) |
| M. tuberculosis | Rv0004 | OG5_166054 | Conserved hypothetical protein |
| M. tuberculosis | Rv0005 | OG5_128755 | DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisome ... |
| M. tuberculosis | Rv0006 | OG5_129568 | DNA gyrase (subunit A) GyrA (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisome ... |
| M. tuberculosis | Rv0009 | OG5_128211 | Probable iron-regulated peptidyl-prolyl cis-trans isomerase A PpiA (PPIase A) (r ... |
| M. tuberculosis | Rv0013 | OG5_128663 | Possible anthranilate synthase component II TrpG (glutamine amidotransferase) |
| M. tuberculosis | Rv0020c | OG5_144358 | Conserved protein with FHA domain, FhaA |
| M. tuberculosis | Rv0021c | OG5_140212 | Conserved hypothetical protein |
| M. tuberculosis | Rv0022c | No group | Probable transcriptional regulatory protein WhiB-like WhiB5 |
| M. tuberculosis | Rv0023 | OG5_239102 | Possible transcriptional regulatory protein |
| M. tuberculosis | Rv0024 | OG5_135136 | Putative secreted protein P60-related protein |
| M. tuberculosis | Rv0025 | OG5_204772 | Conserved hypothetical protein |
| M. tuberculosis | Rv0026 | OG5_204772 | Conserved hypothetical protein |
| M. tuberculosis | Rv0027 | No group | Conserved hypothetical protein |
| M. tuberculosis | Rv0028 | No group | Conserved hypothetical protein |
| M. tuberculosis | Rv0029 | OG5_176750 | Conserved hypothetical protein |
| M. tuberculosis | Rv0030 | No group | Conserved hypothetical protein |
| M. tuberculosis | Rv0031 | No group | Possible remnant of a transposase |
| M. tuberculosis | Rv0032 | OG5_126783 | Possible 8-amino-7-oxononanoate synthase BioF2 (AONS) (8-amino-7-ketopelargonate ... |
| M. tuberculosis | Rv0033 | No group | Probable acyl carrier protein AcpA (ACP) |
| M. tuberculosis | Rv0034 | No group | Conserved hypothetical protein |
| M. tuberculosis | Rv0035 | No group | Probable fatty-acid-CoA ligase FadD34 (fatty-acid-CoA synthetase) (fatty-acid-Co ... |
| M. tuberculosis | Rv0036c | OG5_239103 | Conserved protein |