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Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.
18566 records found | Showing page 1 of 743 (records 1-25) | Number of records to display | Find orthologs in
Organism | Name | Ortholog group | Product | Weight |
---|---|---|---|---|
T. cruzi | TcCLB.510575.180 | OG5_126886 | adenylate kinase, putative | 1143 |
T. cruzi | TcCLB.510243.50 | OG5_126886 | adenylate kinase, putative | 1143 |
T. cruzi | TcCLB.507089.270 | OG5_126968 | dihydrolipoyl dehydrogenase, putative | 1142 |
T. cruzi | TcCLB.511025.110 | OG5_126968 | dihydrolipoyl dehydrogenase, putative | 1142 |
T. cruzi | TcCLB.507011.120 | OG5_146285 | acyl transferase-like protein, putative | 1141 |
T. cruzi | TcCLB.507005.4 | OG5_146285 | acyl transferase-like protein | 1141 |
T. cruzi | TcCLB.511589.120 | OG5_126736 | DNA topoisomerase III, putative | 1139 |
T. cruzi | TcCLB.508851.170 | OG5_126736 | DNA topoisomerase III, putative | 1139 |
T. cruzi | TcCLB.511281.60 | OG5_126685 | pyruvate kinase 2, putative | 1137 |
T. cruzi | TcCLB.507993.390 | OG5_126685 | pyruvate kinase 2, putative | 1137 |
T. cruzi | TcCLB.509331.30 | OG5_126680 | acetyl-CoA synthetase, putative | 1133 |
T. cruzi | TcCLB.504427.110 | OG5_126680 | acetyl-CoA synthetase, putative | 1133 |
T. cruzi | TcCLB.510029.40 | OG5_127419 | DNA-directed RNA polymerase III subunit C11, putative | 1132 |
T. cruzi | TcCLB.511231.50 | OG5_127412 | aminomethyltransferase, mitochondrial, putative | 1132 |
T. cruzi | TcCLB.504069.90 | OG5_126700 | centromere/microtubule binding protein cbf5, putative | 1132 |
T. cruzi | TcCLB.511145.70 | OG5_126700 | centromere/microtubule binding protein cbf5, putative | 1132 |
T. cruzi | TcCLB.509453.40 | OG5_127691 | DNA-directed RNA polymerase I subunit RPB10, putative | 1132 |
T. cruzi | TcCLB.504017.40 | OG5_127412 | aminomethyltransferase, mitochondrial, putative | 1132 |
T. cruzi | TcCLB.506701.10 | OG5_149690 | dihydrolipoamide dehydrogenase, putative | 1132 |
T. cruzi | TcCLB.509379.10 | OG5_149690 | dihydrolipoamide dehydrogenase, putative | 1132 |
T. cruzi | TcCLB.507467.94 | OG5_127688 | hypothetical protein, conserved | 1131 |
T. cruzi | TcCLB.508355.104 | OG5_127688 | hypothetical protein, conserved | 1131 |
T. cruzi | TcCLB.510105.20 | OG5_127234 | exosome complex exonuclease RRP41A | 1130 |
T. cruzi | TcCLB.509715.9 | OG5_127234 | Ribosomal RNA processing protein 41A | 1130 |
T. cruzi | TcCLB.510337.30 | OG5_130883 | adenylosuccinate lyase, putative | 1129 |