Target list

Search results for query: PLoS NTD Query 6 (T. brucei glycolysis)

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  • Score for genes in query #297 (Tbr Dindex >=0.4): 20
  • Score for genes in query #295 (Tbr PDB structure): 20
  • Score for genes in query #300 (Tbr Glycolysis from KEGG): 1000
  • Score for genes in query #301 (uploaded weighted list of enzymes influencing glycolytic flux in Tbr): 0
  • Score for genes in query #293 (Tbr all proteins): 1
  • Score for genes in query #294 (Tbr in Pubmed): 20
  • Score for genes in query #296 (Tbr modbase structures): 10
  • Score for genes in query #298 (Tbr Compound desirability > 0.2): 10
  • Score for genes in query #299 (Tbr assayable): 20

Convert this list of targets into a list of drugs:

Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.

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8299 records found | Showing page 1 of 332 (records 1-25) | Number of records to display | Find orthologs in

  Organism   Name     Ortholog group   Product Weight
T. brucei   Tb927.6.4280   OG5_126628   glyceraldehyde 3-phosphate dehydrogenase, glycosomal 1101
T. brucei   Tb927.6.4300   OG5_126628   glyceraldehyde 3-phosphate dehydrogenase, glycosomal 1101
T. brucei   Tb927.1.700   OG5_126776   phosphoglycerate kinase 1101
T. brucei   Tb927.11.5520   OG5_127002   triosephosphate isomerase 1101
T. brucei   Tb927.1.710   OG5_126776   phosphoglycerate kinase 1081
T. brucei   Tb927.9.8720   OG5_127400   fructose-1,6-bisphosphatase 1081
T. brucei   Tb927.10.2010   OG5_126743   hexokinase 1081
T. brucei   Tb927.10.2020   OG5_126743   hexokinase 1081
T. brucei   Tb927.1.3830   OG5_126980   glucose-6-phosphate isomerase, glycosomal 1071
T. brucei   Tb927.3.3270   OG5_126758   ATP-dependent 6-phosphofructokinase, glycosomal 1071
T. brucei   Tb927.10.2890   OG5_126698   enolase 1071
T. brucei   Tb11.v5.0531   OG5_127143   fructose-bisphosphate aldolase, glycosomal, putative 1071
T. brucei   Tb927.10.6880   OG5_126628   glyceraldehyde 3-phosphate dehydrogenase, cytosolic 1061
T. brucei   Tb927.1.720   OG5_161855   phosphoglycerate kinase 1061
T. brucei   Tb927.11.16730   OG5_126968   dihydrolipoyl dehydrogenase 1051
T. brucei   Tb927.4.5040   OG5_143064   dihydrolipoamide dehydrogenase 1051
T. brucei   Tb927.5.3580   OG5_129378   phosphoglycerate mutase protein, putative 1051
T. brucei   Tb927.3.4390   OG5_149690   dihydrolipoamide dehydrogenase 1051
T. brucei   Tb927.8.7380   OG5_138783   dihydrolipoamide dehydrogenase, point mutation 1051
T. brucei   Tb927.11.16410   OG5_154710   enolase, putative 1051
T. brucei   Tb927.9.9820   OG5_151842   glyceraldehyde-3-phosphate dehydrogenase, putative 1051
T. brucei   Tb927.10.7930   OG5_129051   2,3-bisphosphoglycerate-independent phosphoglycerate mutase 1031
T. brucei   Tb927.8.2520   OG5_126680   acetyl-CoA synthetase, putative 1031
T. brucei   Tb927.10.12700   OG5_127216   pyruvate dehydrogenase E1 alpha subunit, putative 1011
T. brucei   Tb927.6.3050   OG5_127094   aldehyde dehydrogenase family, putative 1011

Showing page 1 (records 1-25) of 332