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Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.
8243 records found | Showing page 1 of 330 (records 1-25) | Number of records to display | Find orthologs in
Organism | Name | Ortholog group | Product | Weight |
---|---|---|---|---|
L. major | LmjF.29.0820 | OG5_127800 | cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin ... | 466 |
L. major | LmjF.23.0050 | OG5_126792 | cyclophilin 11, putative | 436 |
L. major | LmjF.05.0350 | OG5_126785 | trypanothione reductase | 436 |
L. major | LmjF.06.0120 | OG5_127452 | cyclophilin 2 | 436 |
L. major | LmjF.25.0910 | OG5_126792 | cyclophilin a | 436 |
L. major | LmjF.18.0270 | OG5_126888 | glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 | 436 |
L. major | LmjF.06.0860 | OG5_127385 | dihydrofolate reductase-thymidylate synthase | 436 |
L. major | LmjF.36.1960 | OG5_127648 | phosphomannomutase, putative | 416 |
L. major | LmjF.24.0850 | OG5_127002 | triosephosphate isomerase | 401 |
L. major | LmjF.30.2970 | OG5_126628 | glyceraldehyde 3-phosphate dehydrogenase, glycosomal | 401 |
L. major | LmjF.34.1260 | OG5_127218 | mitochondrial DNA polymerase I protein A, putative | 386 |
L. major | LmjF.33.1630 | OG5_126792 | cyclophilin 4, putative | 386 |
L. major | LmjF.19.0550 | OG5_126721 | methionine aminopeptidase, putative,metallo-peptidase, Clan MG, Family M24 | 386 |
L. major | LmjF.32.1580 | OG5_127555 | phosphomannose isomerase | 386 |
L. major | LmjF.30.0880 | OG5_128398 | adenosine kinase, putative | 386 |
L. major | LmjF.21.0250 | OG5_126743 | hexokinase, putative | 386 |
L. major | LmjF.25.1320 | OG5_127141 | serine/threonine protein phosphatase, putative | 386 |
L. major | LmjF.36.1260 | OG5_127143 | fructose-1,6-bisphosphate aldolase | 366 |
L. major | LmjF.23.0270 | OG5_133937 | pteridine reductase 1 | 366 |
L. major | LmjF.28.2280 | OG5_127113 | DNA topoisomerase ii | 366 |
L. major | LmjF.20.0100 | OG5_126776 | phosphoglycerate kinase C, glycosomal | 366 |
L. major | LmjF.33.1690 | OG5_127429 | DNA polymerase delta catalytic subunit, putative | 366 |
L. major | LmjF.18.0990 | OG5_128034 | UDP-glucose pyrophosphorylase | 366 |
L. major | LmjF.18.0090 | OG5_126880 | alpha glucosidase II subunit, putative | 366 |
L. major | LmjF.35.0030 | OG5_126685 | pyruvate kinase | 366 |