Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.
2240 records found | Showing page 1 of 90 (records 1-25) | Number of records to display | Find orthologs in
Organism | Name | Ortholog group | Product | Weight |
---|---|---|---|---|
M. tuberculosis | Rv0885 | OG5_237762 | Conserved hypothetical protein | 597 |
M. tuberculosis | Rv2780 | OG5_127241 | Secreted L-alanine dehydrogenase Ald (40 kDa antigen) (TB43) | 558 |
M. tuberculosis | Rv3290c | OG5_129508 | Probable L-lysine-epsilon aminotransferase Lat (L-lysine aminotransferase) (lysi ... | 553 |
M. tuberculosis | Rv3340 | OG5_130839 | Probable O-acetylhomoserine sulfhydrylase MetC (homocysteine synthase) (O-acetyl ... | 531 |
M. tuberculosis | Rv2629 | No group | Conserved protein | 523 |
M. tuberculosis | Rv2004c | OG5_142650 | Conserved protein | 511 |
M. tuberculosis | Rv0275c | OG5_179227 | Possible transcriptional regulatory protein (possibly TetR-family) | 480 |
M. tuberculosis | Rv2628 | No group | Hypothetical protein | 474 |
M. tuberculosis | Rv2830c | No group | Possible antitoxin VapB22 | 474 |
M. tuberculosis | Rv2626c | OG5_130004 | Hypoxic response protein 1 Hrp1 | 469 |
M. tuberculosis | Rv2035 | No group | Conserved hypothetical protein | 466 |
M. tuberculosis | Rv2497c | OG5_128261 | Probable branched-chain keto acid dehydrogenase E1 component, alpha subunit BkdA | 455 |
M. tuberculosis | Rv2630 | No group | Hypothetical protein | 453 |
M. tuberculosis | Rv2115c | OG5_237684 | Mycobacterial proteasome ATPase Mpa | 446 |
M. tuberculosis | Rv2623 | OG5_126997 | Universal stress protein family protein TB31.7 | 438 |
M. tuberculosis | Rv2627c | OG5_239110 | Conserved protein | 432 |
M. tuberculosis | Rv2032 | OG5_179425 | Conserved protein Acg | 430 |
M. tuberculosis | Rv3131 | OG5_179425 | Conserved protein | 430 |
M. tuberculosis | Rv2624c | OG5_126997 | Universal stress protein family protein | 428 |
M. tuberculosis | Rv1813c | OG5_239134 | Conserved hypothetical protein | 427 |
M. tuberculosis | Rv2711 | OG5_132027 | Iron-dependent repressor and activator IdeR | 424 |
M. tuberculosis | Rv3126c | No group | Hypothetical protein | 415 |
M. tuberculosis | Rv3841 | OG5_127547 | Bacterioferritin BfrB | 404 |
M. tuberculosis | Rv2496c | OG5_128323 | Probable branched-chain keto acid dehydrogenase E1 component, beta subunit BkdB | 404 |
M. tuberculosis | Rv3130c | OG5_133846 | Triacylglycerol synthase (diacylglycerol acyltransferase) Tgs1 | 404 |