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Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.
2253 records found | Showing page 1 of 91 (records 1-25) | Number of records to display | Find orthologs in
Organism | Name | Ortholog group | Product | Weight |
---|---|---|---|---|
M. tuberculosis | Rv0597c | OG5_157133 | Conserved hypothetical protein | 24 |
M. tuberculosis | Rv3111 | OG5_129779 | Probable molybdenum cofactor biosynthesis protein C MoaC1 | 22 |
M. tuberculosis | Rv2257c | OG5_229489 | Conserved protein | 21 |
M. tuberculosis | Rv1627c | OG5_146299 | Probable nonspecific lipid-transfer protein | 20 |
M. tuberculosis | Rv0969 | OG5_126855 | Probable metal cation transporter P-type ATPase CtpV | 19 |
M. tuberculosis | Rv1485 | OG5_127510 | Ferrochelatase HemZ (protoheme ferro-lyase) (heme synthetase) | 19 |
M. tuberculosis | Rv3775 | OG5_139404 | Probable lipase LipE | 19 |
M. tuberculosis | Rv3602c | OG5_129569 | Pantoate--beta-alanine ligase PanC (pantothenate synthetase) (pantoate activatin ... | 19 |
M. tuberculosis | Rv3819 | No group | Unknown protein | 19 |
M. tuberculosis | Rv2032 | OG5_179425 | Conserved protein Acg | 17 |
M. tuberculosis | Rv2875 | OG5_133411 | Major secreted immunogenic protein Mpt70 | 17 |
M. tuberculosis | Rv2591 | OG5_129879 | PE-PGRS family protein PE_PGRS44 | 17 |
M. tuberculosis | Rv2353c | OG5_132376 | PPE family protein PPE39 | 17 |
M. tuberculosis | Rv0295c | No group | Conserved protein | 17 |
M. tuberculosis | Rv0792c | OG5_134860 | Probable transcriptional regulatory protein (probably GntR-family) | 17 |
M. tuberculosis | Rv1259 | OG5_149670 | Probable uracil DNA glycosylase, UdgB | 17 |
M. tuberculosis | Rv2237 | OG5_163412 | Conserved protein | 17 |
M. tuberculosis | Rv2468c | OG5_237676 | Conserved protein | 17 |
M. tuberculosis | Rv2632c | OG5_239144 | Conserved protein | 17 |
M. tuberculosis | Rv3377c | OG5_163665 | Halimadienyl diphosphate synthase | 17 |
M. tuberculosis | Rv1613 | OG5_130207 | Probable tryptophan synthase, alpha subunit TrpA | 17 |
M. tuberculosis | Rv1464 | OG5_128800 | Probable cysteine desulfurase Csd | 16 |
M. tuberculosis | Rv0752c | OG5_136059 | Probable acyl-CoA dehydrogenase FadE9 | 16 |
M. tuberculosis | Rv1270c | No group | Possible lipoprotein LprA | 16 |
M. tuberculosis | Rv0623 | OG5_204775 | Possible antitoxin VapB30 | 16 |